Department of Clinical Laboratory Sciences, University of Texas Medical Branch, Galveston, TX, USA.
Lab Med. 2023 May 2;54(3):287-290. doi: 10.1093/labmed/lmac111.
The aim of this study was to evaluate the effects of Pan Genera Detection (PGD) testing on reducing platelet product wastage and transfusion service costs.
We conducted a retrospective cross-sectional study comparing the number of platelet apheresis units wasted before (March 2017 to February 2019) and after (March 2019 to February 2021) PGD implementation. The PGD testing was performed before transfusion on days 6 and 7. Cost analysis considered the costs of platelet units wasted ($500.00/unit) and PGD test supplies and performance (estimated $26.50 per test). Paired samples t-test was used to compare platelet wastage pre- and post-PGD implementation.
The number of wasted platelet units decreased from pre-PGD (419) to post-PGD (195), representing a significant decrease in platelet wastage from 17.5% to 9.2% (P < .0001). During the post-PGD period, 366 and 133 units were tested on days 6 and 7, with 28 and 36 units discarded each day, allowing transfusion of an additional 302 platelet units. Costs from platelet wastage decreased from $209,500.00 pre-PGD to $97,500.00 post-PGD.
Our results showed that PGD testing effectively reduced platelet wastage, extended platelet availability, and reduced transfusion service costs.
本研究旨在评估 Pan Genera Detection（PGD）检测对减少血小板制品浪费和输血服务成本的影响。
我们进行了一项回顾性横断面研究，比较了实施 PGD 检测前后（2017 年 3 月至 2019 年 2 月和 2019 年 3 月至 2021 年 2 月）血小板单采单位的浪费数量。PGD 检测在输血前第 6 天和第 7 天进行。成本分析考虑了浪费的血小板单位成本（500.00 美元/单位）和 PGD 检测用品和性能成本（估计每次检测 26.50 美元）。采用配对样本 t 检验比较 PGD 实施前后的血小板浪费量。
浪费的血小板单位数量从 PGD 前（419）减少到 PGD 后（195），表明血小板浪费从 17.5%显著减少到 9.2%（P<0.0001）。在 PGD 后期间，第 6 天和第 7 天分别检测了 366 和 133 个单位，每天丢弃 28 和 36 个单位，可额外输注 302 个血小板单位。由于血小板浪费而导致的成本从 PGD 前的 209500.00 美元减少到 PGD 后的 97500.00 美元。
我们的结果表明，PGD 检测有效减少了血小板浪费，延长了血小板的可用性，并降低了输血服务成本。
