Department of Integrated Health Science, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Faculty of Science and Engineering, Waseda University, Tokyo, Japan.
Phys Med. 2022 Nov;103:66-73. doi: 10.1016/j.ejmp.2022.09.017. Epub 2022 Oct 13.
Although real-time imaging of the high-activity iridium-192 (Ir-192) source position during high-dose-rate (HDR) brachytherapy using a high-energy gamma camera system is a promising approach, the energy window was not optimized for spatial resolution or scatter fraction.
By using a list-mode data-acquisition system that can acquire energy information of a cerium-doped yttrium aluminum perovskite (YA1O: YAP(Ce)) gamma camera, we tried to optimize the energy window's setting to improve the spatial resolution and reduce scatter fraction.
The spatial resolution was highest for the central energy of the window at ∼300 keV. The scatter fraction was also smallest for the central energy of the window at ∼300 keV, and the scatter fraction was more than 48 % smaller than that for the full energy window.
We clarified that the spatial resolution can be improved and the scatter fraction can be reduced through optimizing the energy window of the YAP(Ce) gamma camera by setting the central energy of the window to ∼300 keV for HDR brachytherapy.
尽管使用高能伽马相机系统实时成像高活度铱-192(Ir-192)源位置是一种很有前途的方法,但该能量窗并未针对空间分辨率或散射分数进行优化。
通过使用可获取掺铈钇铝石榴石(Ce:YAP)伽马相机的列表模式数据采集系统,我们尝试优化能量窗的设置,以提高空间分辨率并降低散射分数。
窗口中心能量约为 300keV 时,空间分辨率最高。窗口中心能量约为 300keV 时,散射分数也最小,比全能量窗的散射分数小 48%以上。
我们证实,通过将窗口的中心能量设置为约 300keV,可优化 YAP(Ce)伽马相机的能量窗,从而提高空间分辨率并降低 HDR 近距离治疗中的散射分数。