Rosmarin David H, Kaufman Caroline C, Ford Stephanie Friree, Keshava Poorvi, Drury Mia, Minns Sean, Marmarosh Cheri, Chowdhury Avijit, Sacchet Matthew D
Spirituality & Mental Health Program, McLean Hospital, Belmont, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Spirituality & Mental Health Program, McLean Hospital, Belmont, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
J Psychiatr Res. 2022 Dec;156:100-113. doi: 10.1016/j.jpsychires.2022.10.003. Epub 2022 Oct 7.
Prior research highlights the importance of spirituality/religion (S/R) as it relates to several aspects of mental health and clinical interventions. This research has been expanded to include the concurrent examination of neurobiological correlates of S/R to elucidate potential biological mechanisms. However, the majority of neurobiological research on S/R has neglected mental health, and the relationship across all three of these domains (S/R, mental health, and neurobiology) remains unclear. This study systematically reviewed research concurrently examining S/R, mental health, and neurobiology, and rated the methodological quality of included studies. Eighteen identified studies were then included in an integrated literature review and discussion, regarding the neurobiological correlates of S/R as it pertains to depression, anxiety, alcohol/substance misuse, and psychosis. The majority of studies demonstrated moderate to high methodological quality. Findings highlight the need for additional studies in this area as well as research that includes validated assessment of S/R.
先前的研究强调了精神性/宗教信仰（S/R）与心理健康及临床干预若干方面的相关性。这项研究已扩展至同时考察S/R的神经生物学关联，以阐明潜在的生物学机制。然而，大多数关于S/R的神经生物学研究忽略了心理健康，这三个领域（S/R、心理健康和神经生物学）之间的关系仍不明确。本研究系统回顾了同时考察S/R、心理健康和神经生物学的研究，并对纳入研究的方法学质量进行了评级。随后，18项已识别的研究被纳入一篇综合文献综述与讨论，内容涉及S/R与抑郁症、焦虑症、酒精/物质滥用及精神病的神经生物学关联。大多数研究显示出中等至高的方法学质量。研究结果凸显了该领域开展更多研究的必要性，以及纳入经过验证的S/R评估的研究的必要性。
