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腹外疝修补术中的解剖分离与短期疗效应用。

Application of Component Separation and Short-Term Outcomes in Ventral Hernia Repairs.

机构信息

University of Michigan Medical School, Ann Arbor, Michigan.

Department of Surgery, University of Michigan, Ann Arbor, Michigan; Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, Michigan.

出版信息

J Surg Res. 2023 Feb;282:1-8. doi: 10.1016/j.jss.2022.09.007. Epub 2022 Oct 13.

Abstract

INTRODUCTION

Component separation (CS) techniques have evolved in recent years. How surgeons apply the various CS techniques, anterior component separation (aCS) versus posterior component separation (pCS), by patient and hernia-specific factors remain unknown in the general population. Improving the quality of ventral hernia repair (VHR) on a large scale requires an understanding of current practice variations and how these variations ultimately affect patient care. In this study, we examine the application of CS techniques and the associated short-term outcomes while taking into consideration patient and hernia-specific factors.

METHODS

We retrospectively reviewed a clinically rich statewide hernia registry, the Michigan Surgical Quality Collaborative Hernia Registry, of persons older than 18 y who underwent VHR between January 2020 and July 2021. The exposure of interest was the use of CS. Our primary outcome was a composite end point of 30-d adverse events including any complication, emergency department visit, readmission, and reoperation. Our secondary outcome was surgical site infection (SSI). Multivariable logistic regression examined the association of CS use, 30-d adverse events, and SSI with patient-, hernia-, and operative-specific variables. We performed a sensitivity analysis evaluating for differences in application and outcomes of the posterior and aCS techniques.

RESULTS

A total of 1319 patients underwent VHR, with a median age (interquartile range) of 55 y (22), 641 (49%) female patients, and a median body mass index of 32 (9) kg/m. CS was used in 138 (11%) patients, of which 101 (73%) were pCS and 37 (27%) were aCS. Compared to patients without CS, patients undergoing a CS had larger median hernia widths (2.5 cm (range 0.01-23 cm) versus 8 cm (1-30 cm), P < 0.001). Of the CS cases, 49 (36%) performed in hernias less than 6 cm in size. Following multivariate regression, factors independently associated with the use of a CS were diabetes (odds ratio [OR]: 2.00, 95% confidence interval [CI]: 1.19-3.36), previous hernia repair (OR: 1.88, 95% CI: 1.20-2.96), hernia width (OR: 1.28, 95% CI: 1.22-1.34), and an open approach (OR: 3.83, 95% CI: 2.24-6.53). Compared to patients not having a CS, use of a CS was associated with increased odds of 30-d adverse events (OR: 1.88 95% CI: 1.13-3.12) but was not associated with SSI (OR: 1.95, 95% CI: 0.74-4.63). Regression analysis demonstrated no differences in 30-d adverse events or SSI between the pCS and aCS techniques.

CONCLUSIONS

This is the first population-level report of patients undergoing VHR with concurrent posterior or aCS. These data suggest wide variation in the application of CS in VHR and raises a concern for potential overutilization in smaller hernias. Continued analysis of CS application and the associated outcomes, specifically recurrence, is necessary and underway.

摘要

简介

近年来, 组件分离(CS)技术不断发展。 外科医生如何根据患者和疝的具体因素应用各种 CS 技术,包括前组件分离(aCS)与后组件分离(pCS),在普通人群中尚不清楚。 要大规模提高腹疝修复(VHR)的质量, 需要了解当前实践中的差异,以及这些差异最终如何影响患者护理。 在这项研究中,我们考察了 CS 技术的应用以及考虑到患者和疝的具体因素时的短期结果。

方法

我们回顾性分析了密歇根手术质量协作疝登记处(Michigan Surgical Quality Collaborative Hernia Registry)中的一个临床资料丰富的全州疝登记处,该登记处纳入了 2020 年 1 月至 2021 年 7 月期间年龄大于 18 岁接受 VHR 的患者。感兴趣的暴露因素是 CS 的使用。我们的主要结局是 30 天不良事件的复合终点,包括任何并发症、急诊就诊、再入院和再次手术。我们的次要结局是手术部位感染(SSI)。多变量逻辑回归分析了 CS 使用、30 天不良事件和 SSI 与患者、疝和手术特定变量的关系。我们进行了敏感性分析,评估了后 CS 和 aCS 技术的应用和结局的差异。

结果

共纳入 1319 例接受 VHR 的患者,中位年龄(四分位间距)为 55 岁(22),641 例(49%)为女性患者,中位体重指数为 32(9)kg/m2。138 例(11%)患者使用了 CS,其中 101 例(73%)为 pCS,37 例(27%)为 aCS。与未使用 CS 的患者相比,使用 CS 的患者的疝宽度中位数更大(2.5cm(范围 0.01-23cm)与 8cm(1-30cm),P<0.001)。CS 病例中,49 例(36%)在疝小于 6cm 时进行。多变量回归后,与使用 CS 相关的独立因素包括糖尿病(比值比[OR]:2.00,95%置信区间[CI]:1.19-3.36)、既往疝修补术(OR:1.88,95%CI:1.20-2.96)、疝宽度(OR:1.28,95%CI:1.22-1.34)和开放手术(OR:3.83,95%CI:2.24-6.53)。与未使用 CS 的患者相比,使用 CS 与 30 天不良事件的几率增加相关(OR:1.88,95%CI:1.13-3.12),但与 SSI 无关(OR:1.95,95%CI:0.74-4.63)。回归分析表明,pCS 和 aCS 技术之间 30 天不良事件或 SSI 无差异。

结论

这是首次在接受 VHR 治疗的人群中同时应用后 CS 和 aCS 的人群报告。这些数据表明,CS 在 VHR 中的应用存在广泛差异,并引起了对在较小疝中潜在过度使用的关注。需要对 CS 的应用及其相关结果(特别是复发)进行进一步分析。

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