用于检测詹姆斯敦峡谷病毒抗体的血凝素的生产与应用。
Production and use of a hemagglutinin for detecting antibody to Jamestown Canyon virus.
作者信息
Grimstad P R, Artsob H, Karabatsos N, Calisher C H
出版信息
J Clin Microbiol. 1987 Aug;25(8):1557-9. doi: 10.1128/jcm.25.8.1557-1559.1987.
Abstract
A procedure was developed for producing a hemagglutinin for the California serogroup (family Bunyaviridae, genus Bunyavirus) virus Jamestown Canyon, a human pathogen. Serum samples from humans putatively infected with this virus or with La Crosse virus were tested by hemagglutination inhibition. Each antigen detected antibody to the respective virus, with little cross-reactivity. These results suggest that both antigens should be used when the hemagglutination inhibition test is applied to the diagnosis of human infections with California serogroup viruses in North America.
摘要
已开发出一种程序，用于生产针对加利福尼亚血清群（布尼亚病毒科，布尼亚病毒属）病毒詹姆斯敦峡谷株的血凝素，该病毒是一种人类病原体。通过血凝抑制试验对疑似感染该病毒或拉克罗斯病毒的人类血清样本进行检测。每种抗原都能检测到针对相应病毒的抗体，交叉反应很少。这些结果表明，当血凝抑制试验用于诊断北美人类感染加利福尼亚血清群病毒时，两种抗原都应使用。
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