Lamb J, Anderson T J, Dixon M J, Levack P A
J Clin Pathol. 1987 Jul;40(7):705-9. doi: 10.1136/jcp.40.7.705.
In a six year period up to the end of December 1985 fine needle aspiration cytology specimens of the breast were obtained from 562 apparently healthy women invited to participate in a breast cancer screening programme. Of these, 397 had a biopsy and 173 cancers were confirmed histologically. For the diagnosis of cancer, the procedure was less successful than in symptomatic cases. The main factors influencing success were the aspirator, the small size of many cancers, and the occult nature of the lesions seen only on mammography. Retrospective analysis of the figures shows that combining the results of FNA cytology in a triple assessment with physical and mammographical findings for restricted selection means that the number of benign biopsy specimens could be reduced considerably.
在截至1985年12月底的六年时间里，从562名受邀参加乳腺癌筛查项目的貌似健康的女性身上获取了乳腺细针穿刺细胞学标本。其中，397人接受了活检，经组织学证实有173例癌症。对于癌症的诊断，该程序不如在有症状的病例中那么成功。影响成功的主要因素包括抽吸器、许多癌症体积较小以及仅在乳房X光检查中可见的病变的隐匿性。对这些数据的回顾性分析表明，在三重评估中将细针穿刺细胞学结果与体格检查和乳房X光检查结果相结合以进行有限选择，意味着良性活检标本的数量可以大幅减少。
