Department of Orthodontics, National Clinical Research Center for Oral Diseases, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Pain Res Manag. 2022 Sep 30;2022:1039393. doi: 10.1155/2022/1039393. eCollection 2022.
Temporomandibular disorders (TMDs) refer to a group of heterogenous musculoskeletal diseases with diverse clinical symptoms and an undetermined aetiology. The psychological profiles were closely related to the onset and treatment outcomes of TMDs.
To examine the relevance between psychological profiles and different symptoms of TMDs in preorthodontic patients.
The study was conducted among 570 preorthodontic patients. TMDs symptoms were recorded by the Diagnostic Criteria for TMD (DC/TMD) symptom questionnaire. The seven-item Generalized Anxiety Disorder Scale (GAD-7), the nine-item Patient Health Questionnaire (PHQ-9), and the Pain Catastrophizing Scale (PCS) were used for the evaluation of anxiety, depression, and pain catastrophizing levels. The relevance of three psychological profiles with TMDs and subtypes was evaluated with Spearman's rank correlation test and logistic regression analysis ( < 0.05).
34.56% of the enrolled preorthodontic patients were diagnosed with TMDs. Scores of GAD-7, PHQ-9, and PCS were significantly higher in the TMDs group than in the non-TMDs group. Participants with anxiety, depression, or high pain catastrophizing had a higher prevalence of both pain-related TMDs symptoms and intra-articular TMDs symptoms. The correlations among pain-related TMDs, intra-articular TMDs, and scores on the psychological scales were significant ( < 0.05). The adjusted logistic regression model revealed that anxiety, depression, and high pain catastrophizing were significant risk factors for TMDs with an odds ratio (OR) of 2.196, 1.741, and 1.601, respectively. Depression was associated with higher pain-related TMDs prevalence (OR = 2.136), while anxiety and depression were associated with higher intra-articular TMDs prevalence (OR = 2.341 and 1.473).
Anxiety, depression, and high pain catastrophizing were comorbid psychological conditions of TMDs. Depression was the top risk factor for pain-related TMDs, while anxiety rendered the highest risk for intra-articular TMDs. Inclusion of psychological assessments in preorthodontic evaluation might yield great benefits in TMDs screening.
颞下颌关节紊乱病(TMD)是一组具有不同临床表现且病因不明的异质性肌肉骨骼疾病。心理特征与 TMD 的发病和治疗结果密切相关。
探讨正畸前患者的心理特征与 TMD 不同症状之间的关系。
研究纳入了 570 名正畸前患者。使用 TMD 诊断标准(DC/TMD)症状问卷记录 TMD 症状。采用 7 项广泛性焦虑障碍量表(GAD-7)、9 项患者健康问卷(PHQ-9)和疼痛灾难化量表(PCS)评估焦虑、抑郁和疼痛灾难化水平。采用 Spearman 秩相关检验和逻辑回归分析( < 0.05)评估三种心理特征与 TMD 及其亚型的相关性。
研究纳入的正畸前患者中,34.56%被诊断为 TMD。TMD 组的 GAD-7、PHQ-9 和 PCS 评分均显著高于非 TMD 组。有焦虑、抑郁或高疼痛灾难化的患者,其疼痛相关 TMD 症状和关节内 TMD 症状的发生率均较高。疼痛相关 TMD、关节内 TMD 与心理量表评分之间的相关性具有统计学意义( < 0.05)。调整后的逻辑回归模型显示,焦虑、抑郁和高疼痛灾难化是 TMD 的显著危险因素,其比值比(OR)分别为 2.196、1.741 和 1.601。抑郁与较高的疼痛相关 TMD 患病率相关(OR=2.136),而焦虑和抑郁与较高的关节内 TMD 患病率相关(OR=2.341 和 1.473)。
焦虑、抑郁和高疼痛灾难化是 TMD 的共患心理状况。抑郁是疼痛相关 TMD 的首要危险因素,而焦虑则是关节内 TMD 的最高危险因素。在正畸前评估中纳入心理评估可能会在 TMD 筛查中带来巨大益处。