Rezaei Fatemeh, Seif Mozhgan, Fattahi Mohammad Reza, Gandomkar Abdullah, Hasanzadeh Jafar
Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran.
Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran J Public Health. 2022 Jul;51(7):1667-1676. doi: 10.18502/ijph.v51i7.10101.
An effective strategy for primary prevention of Cardiovascular Disease (CVD) is accurate diagnosis and the subsequent evidence-based treatment for high-risk people. This study aimed to estimate the 10-year risk of CVD and its related factors.
The baseline data of 8138 participants of the Pars cohort study (PCS) in southern Iran were used. Risk scores were calculated using the updated 2019 WHO CVD risk prediction charts. The scores were determined based on age, gender, current smoking status, systolic blood pressure (SBP), diabetes status, and total serum cholesterol. Demographic and socioeconomic variables, physical activity, and anthropometric indices were measured and analyzed. Multivariable logistic regression was applied to estimate the adjusted odds ratio (aOR) and 95% confidence intervals (CI).
The mean (SD) age of the participants was 51.65 (9.06) years, and 53.44% were female. The 10-year CVD risk for 23.89% of participants was ≥10%. The prevalence of hypertension, diabetes, hypercholesterolemia, and smoking was 12.79%, 8.38%, 12.80%, and 14.41%, respectively. Having abdominal obesity, having low or moderate physical activity, being illiterate or having diplomas or lower degrees, and being in the third quartile of the wealth score group were associated with a higher 10-year risk of CVD.
About one-fourth of the participants had moderate risk and higher. Due to the relatively high prevalence of CVD risk factors in the middle-aged population, the modifiable risk factors are recommended to be adjusted. Additionally, individual- and community-based educational policies are essential to create a healthy lifestyle.
心血管疾病（CVD）一级预防的有效策略是对高危人群进行准确诊断并随后进行循证治疗。本研究旨在评估CVD的10年风险及其相关因素。
使用了伊朗南部帕尔斯队列研究（PCS）8138名参与者的基线数据。风险评分采用更新后的2019年世界卫生组织CVD风险预测图表进行计算。评分根据年龄、性别、当前吸烟状况、收缩压（SBP）、糖尿病状况和总血清胆固醇确定。测量并分析了人口统计学和社会经济变量、身体活动及人体测量指标。应用多变量逻辑回归来估计调整后的优势比（aOR）和95%置信区间（CI）。
参与者的平均（标准差）年龄为51.65（9.06）岁，女性占53.44%。23.89%的参与者10年CVD风险≥10%。高血压、糖尿病、高胆固醇血症和吸烟的患病率分别为12.79%、8.38%、12.80%和14.41%。腹部肥胖、身体活动水平低或中等、文盲或拥有文凭及以下学历以及处于财富评分组的第三个四分位数与较高的10年CVD风险相关。
约四分之一的参与者有中度及更高风险。由于中年人群中CVD风险因素的患病率相对较高，建议对可改变的风险因素进行调整。此外，基于个体和社区的教育政策对于建立健康的生活方式至关重要。
