Liu Chen, Wang Yewen, Zhao Ai-Rong, Hu Feng-Ai, Fan Qizhong, Han Guoxiu, Ding Guojian, Fu Tingliang, Geng Lei, Yin Hongshan
The Department of Pediatric Surgery, Binzhou Medical University Hospital, Binzhou, China.
The Department of Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Front Surg. 2022 Sep 28;9:896542. doi: 10.3389/fsurg.2022.896542. eCollection 2022.
Anastomotic techniques are of vital importance in restoring gastrointestinal continuity after resection. An alternative asymmetric figure-of-eight single-layer suture anastomotic technique was introduced and its effects were evaluated in an porcine model. Twelve 15-cm grossly healthy small intestine segments from a porcine cadaver were harvested and randomly divided into asymmetric figure-of-eight single-layer suture (figure-of-eight suture) and single-layer interrupted suture technique (interrupted suture) groups ( = 6 in each group). The anastomosed bowel was infused with methylene blue solution to test anastomotic leakage. Anastomosis construction time, leakage, and suture material cost were recorded and analyzed statistically using Fisher's exact test and Student's -test. One anastomotic leakage occurred (16.67%) in the figure-of-eight suture group, and two (33.33%) in the interrupted suture group ( > 0.9999). The anastomosis construction time was relatively short in the figure-of-eight suture group, but the difference did not reach a statistically significant level between the two groups. The mean number of suture knots and the cost of suture material in the figure-of-eight suture group were significantly decreased in comparison to the interrupted suture group (15.67 ± 3.30 vs. 22.17 ± 2.03, 167.11 ± 35.20 vs. 236.45 ± 21.70 CNY, < 0.01, respectively). Our results suggested that the alternative asymmetric figure-of-eight suture technique was safe and economic for intestinal anastomosis. An experiment is required to elucidate the effects of this suture technique on the physiological anastomotic healing process.
吻合技术在切除术后恢复胃肠道连续性方面至关重要。本文介绍了一种替代性的不对称八字形单层缝合吻合技术,并在猪模型中评估了其效果。从猪尸体上获取12段15厘米长外观健康的小肠段,随机分为不对称八字形单层缝合(八字形缝合)组和单层间断缝合技术(间断缝合)组(每组n = 6)。向吻合后的肠管注入亚甲蓝溶液以检测吻合口漏。记录吻合构建时间、漏口情况及缝合材料成本,并采用Fisher精确检验和Student's t检验进行统计学分析。八字形缝合组发生1例吻合口漏(16.67%),间断缝合组发生2例(33.33%)(P>0.9999)。八字形缝合组的吻合构建时间相对较短,但两组间差异未达到统计学显著水平。与间断缝合组相比,八字形缝合组的平均缝线结数和缝合材料成本显著降低(分别为15.67±3.30对22.17±2.03,167.11±35.20对236.45±21.70元人民币,P均<0.01)。我们的结果表明,替代性的不对称八字形缝合技术用于肠吻合是安全且经济的。需要进行进一步实验以阐明这种缝合技术对生理性吻合口愈合过程的影响。