Upadhyaya Susmita, Agarwal Mayank, Upadhyaya Ashutosh, Pathania Monika, Dhar Minakshi
Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
General Physician, Evergreen Hospital Pvt. Ltd, Parasi, NPL.
Cureus. 2022 Sep 11;14(9):e29018. doi: 10.7759/cureus.29018. eCollection 2022 Sep.
Rhupus syndrome, a rare coexistence of systemic lupus erythematosus (SLE) and rheumatoid arthritis, is characterized by symmetrical erosive polyarthritis and permanent deformities in addition to the clinical and serological characteristics of SLE. Its prognosis is further complicated by neurological and hematological involvement, which dramatically lowers patients' perceptions of their quality of life in terms of their health. Rhupus individuals have significantly less kidney involvement than SLE patients do. We present a case of a young female who had symmetric, bilateral, erosive polyarthritis for one and a half years preceding the signs and symptoms of SLE, which occurred about six months later.
Rhupus综合征是系统性红斑狼疮(SLE)和类风湿性关节炎罕见的共存情况,其特征除了有SLE的临床和血清学特征外,还伴有对称性侵蚀性多关节炎和永久性畸形。神经和血液系统受累使该病的预后更加复杂,这极大地降低了患者对自身健康方面生活质量的认知。Rhupus患者的肾脏受累情况明显少于SLE患者。我们报告一例年轻女性病例,该患者在出现SLE的体征和症状约六个月前,已有对称、双侧侵蚀性多关节炎达一年半时间。