三级疼痛诊所网络中的慢性非癌性疼痛管理:一项回顾性研究

Chronic Non-cancer Pain Management in a Tertiary Pain Clinic Network: a Retrospective Study.

作者信息

Latina Roberto, Varrassi Giustino, Di Biagio Ettore, Giannarelli Diana, Gravante Francesco, Paladini Antonella, D'Angelo Daniela, Iacorossi Laura, Martella Cristina, Alvaro Rosaria, Ivziku Dhurata, Veronese Nicola, Barbagallo Mario, Marchetti Anna, Notaro Paolo, Terrenato Irene, Tarsitani Gianfranco, De Marinis Maria Grazia

机构信息

Department of Health Promotion Science, Maternal and Infant Care, Internal Medicine, and Medical Specialities (PROMISE), University of Palermo, Palermo, Italy.

Paolo Procacci Foundation, Rome, Italy.

出版信息

Pain Ther. 2023 Feb;12(1):151-164. doi: 10.1007/s40122-022-00446-1. Epub 2022 Oct 17.

Abstract

INTRODUCTION

Chronic pain is a distressing condition that should be treated in specialized pain clinics. Pain clinics offer a holistic, evidence-based approach, including pharmacological, complementary, and invasive treatments. This study aimed to provide preliminary information regarding chronic pain treatments and identify reasons for accessing an important hub-spoke pain clinic network.

METHODS

A retrospective multicenter cross-sectional study was carried out. A total of 1606 patients' records were included. Patients were selected from the 26 pain clinics of a single region in Italy. Univariate and multivariate logistic regression models were used.

RESULTS

Multivariate models showed that the use of opioids were considered effective for severe or moderate pain [odds ratio (OR) 0.41; 95% 0.33-0.51], while the use of invasive treatments (OR 2.45; 95% 1.95-3.06) and the use of complementary therapy (OR 1.87; 95% 1.38-2.51) were associated with severe or moderate pain. Overall, age, sex, nonsteroidal anti-inflammatory drugs (NSAID) use, a combination of NSAIDs, complementary therapies, and a combination of opioids and invasive treatments did not seem to be significantly associated with the nature of pain. Multivariate models confirmed that clinical parameters such as the nature of pain, multi-diagnosis, more than one site of pain, treatments, and general practitioner, but not the severity of pain and use of invasive treatments, had an impact on the choice of a pain clinic.

CONCLUSION

Opioids are useful in managing moderate or severe chronic pain. Multimodal approaches are used for the management of chronic pain. Moreover, it is not clear how patients are addressed to access different pain clinics (spoke versus hub) networks. More widespread adoption is needed for an interdisciplinary approach to managing chronic pain and adopting guideline recommendations, and rigorous research is required to provide more substantial evidence and support clinical practice.

摘要

引言

慢性疼痛是一种令人痛苦的病症,应在专业疼痛诊所进行治疗。疼痛诊所提供全面的、基于证据的治疗方法,包括药物治疗、辅助治疗和侵入性治疗。本研究旨在提供有关慢性疼痛治疗的初步信息,并确定患者选择进入一个重要的枢纽-辐条式疼痛诊所网络的原因。

方法

开展了一项回顾性多中心横断面研究。共纳入1606例患者的记录。患者选自意大利单个地区的26家疼痛诊所。使用了单变量和多变量逻辑回归模型。

结果

多变量模型显示,使用阿片类药物被认为对重度或中度疼痛有效[比值比(OR)0.41;95%置信区间0.33-0.51],而使用侵入性治疗(OR 2.45;95%置信区间1.95-3.06)和辅助治疗(OR 1.87;95%置信区间1.38-2.51)与重度或中度疼痛相关。总体而言,年龄、性别、非甾体抗炎药(NSAID)的使用、NSAIDs的联合使用、辅助治疗以及阿片类药物与侵入性治疗的联合使用似乎与疼痛性质无显著关联。多变量模型证实,诸如疼痛性质、多诊断、多个疼痛部位、治疗方法以及全科医生等临床参数,但不包括疼痛严重程度和侵入性治疗的使用,会影响对疼痛诊所的选择。

结论

阿片类药物对管理中度或重度慢性疼痛有用。多模式方法用于慢性疼痛的管理。此外,尚不清楚患者是如何被引导进入不同的疼痛诊所(辐条式与枢纽式)网络的。跨学科方法管理慢性疼痛并采用指南建议需要更广泛地应用,并且需要进行严谨的研究以提供更充分的证据并支持临床实践。

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