Department of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.
Adv Exp Med Biol. 2022;1386:185-221. doi: 10.1007/978-3-031-08491-1_7.
Based on genome analyses, it has been estimated that more than half of the bacteria have made an important investment into motility since they possess genes encoding the flagellar motor, the flagellum, chemosensory pathways and chemoreceptors. The metabolic burden associated with gene maintenance, protein synthesis and operating these systems is very important. A central question is thus to establish the physiological benefits that compensate such an important investment. In this chapter, we illustrate that benefits are multiple and diverse, including access to nutrients and preferred niches, biofilm formation and bacterial dispersal. There is also evidence that the complete range of advantages still remains to be defined. In these research efforts, Pseudomonas aeruginosa (PA) has played a central role and is among the central model species. Research conducted on PA had a significant impact in the field and has motivated many experiments in the study of other model bacterial species.
基于基因组分析,据估计,超过一半的细菌在运动性方面进行了重要的投资,因为它们拥有编码鞭毛马达、鞭毛、化学感应途径和化学感受器的基因。与基因维持、蛋白质合成和操作这些系统相关的代谢负担非常重要。因此,一个核心问题是确定补偿这种重要投资的生理益处。在本章中,我们说明这些益处是多样的,包括获得营养物质和偏好的小生境、生物膜形成和细菌分散。也有证据表明,完整的优势范围仍有待确定。在这些研究努力中,铜绿假单胞菌(PA)发挥了核心作用,是中心模式物种之一。对 PA 的研究在该领域产生了重大影响,并激发了许多对其他模式细菌物种的研究实验。