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鞭毛、趋化性和表面感应。

Flagella, Chemotaxis and Surface Sensing.

机构信息

Department of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.

出版信息

Adv Exp Med Biol. 2022;1386:185-221. doi: 10.1007/978-3-031-08491-1_7.

DOI:10.1007/978-3-031-08491-1_7
PMID:36258073
Abstract

Based on genome analyses, it has been estimated that more than half of the bacteria have made an important investment into motility since they possess genes encoding the flagellar motor, the flagellum, chemosensory pathways and chemoreceptors. The metabolic burden associated with gene maintenance, protein synthesis and operating these systems is very important. A central question is thus to establish the physiological benefits that compensate such an important investment. In this chapter, we illustrate that benefits are multiple and diverse, including access to nutrients and preferred niches, biofilm formation and bacterial dispersal. There is also evidence that the complete range of advantages still remains to be defined. In these research efforts, Pseudomonas aeruginosa (PA) has played a central role and is among the central model species. Research conducted on PA had a significant impact in the field and has motivated many experiments in the study of other model bacterial species.

摘要

基于基因组分析,据估计,超过一半的细菌在运动性方面进行了重要的投资,因为它们拥有编码鞭毛马达、鞭毛、化学感应途径和化学感受器的基因。与基因维持、蛋白质合成和操作这些系统相关的代谢负担非常重要。因此,一个核心问题是确定补偿这种重要投资的生理益处。在本章中,我们说明这些益处是多样的,包括获得营养物质和偏好的小生境、生物膜形成和细菌分散。也有证据表明,完整的优势范围仍有待确定。在这些研究努力中,铜绿假单胞菌(PA)发挥了核心作用,是中心模式物种之一。对 PA 的研究在该领域产生了重大影响,并激发了许多对其他模式细菌物种的研究实验。

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2
Flagella hook protein FlgE is a novel vaccine candidate of Pseudomonas aeruginosa identified by a genomic approach.鞭毛钩状蛋白 FlgE 是一种通过基因组方法鉴定的铜绿假单胞菌新型候选疫苗。
Vaccine. 2021 Apr 22;39(17):2386-2395. doi: 10.1016/j.vaccine.2021.03.051. Epub 2021 Mar 26.
3
Evidence for Pentapeptide-Dependent and Independent CheB Methylesterases.
环二鸟苷单磷酸(c-di-GMP)合成与降解的极性
Microlife. 2023 Apr 5;4:uqad014. doi: 10.1093/femsml/uqad014. eCollection 2023.
依赖五肽和不依赖五肽的 CheB 甲基酯酶的证据。
Int J Mol Sci. 2020 Nov 11;21(22):8459. doi: 10.3390/ijms21228459.
4
Pfam: The protein families database in 2021.Pfam:2021 年的蛋白质家族数据库。
Nucleic Acids Res. 2021 Jan 8;49(D1):D412-D419. doi: 10.1093/nar/gkaa913.
5
Sensing of autoinducer-2 by functionally distinct receptors in prokaryotes.原核生物中功能不同的受体对自身诱导物-2 的感应。
Nat Commun. 2020 Oct 23;11(1):5371. doi: 10.1038/s41467-020-19243-5.
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Flagella by numbers: comparative genomic analysis of the supernumerary flagellar systems among the Enterobacterales.数量决定鞭毛:肠杆菌目中多余鞭毛系统的比较基因组分析。
BMC Genomics. 2020 Sep 29;21(1):670. doi: 10.1186/s12864-020-07085-w.
7
Surface Sensing and Adaptation in Bacteria.细菌中的表面感知与适应
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