Ball A J, Carr T W, Gillespie W A, Kelly M, Simpson R A, Smith P J
J Urol. 1987 Sep;138(3):491-4. doi: 10.1016/s0022-5347(17)43237-x.
The value of postoperative bladder irrigation with the antiseptic agent chlorhexidine was assessed in a randomized prospective controlled study of men after transurethral operations. In patients with sterile preoperative urine the incidence of postoperative bacteriuria was 12.8 per cent, compared to 36.7 per cent in control patients. The difference is significant (chi-square 5.54, p less than 0.02). On the other hand, chlorhexidine irrigation did not eliminate pre-existing infection. Small amounts of chlorhexidine were demonstrated in the blood of some patients. There was no evidence of damage to the bladder and no toxic side effects.
在一项针对经尿道手术后男性患者的随机前瞻性对照研究中，评估了使用抗菌剂洗必泰进行术后膀胱冲洗的价值。术前尿液无菌的患者术后菌尿发生率为12.8%，而对照患者为36.7%。差异具有统计学意义（卡方值5.54，p<0.02）。另一方面，洗必泰冲洗并不能消除术前已存在的感染。在一些患者的血液中检测到少量洗必泰。没有证据表明对膀胱有损害，也没有毒性副作用。
