肾腺癌与终末期肾病
Renal adenocarcinoma and end stage kidney disease.
作者信息
Boileau M, Foley R, Flechner S, Weinman E
出版信息
J Urol. 1987 Sep;138(3):603-6. doi: 10.1016/s0022-5347(17)43271-x.
The association of end stage kidney disease with cystic degeneration and renal adenocarcinoma was first recognized in 1977. Since then a number of reports have confirmed this relationship. Duration of dialysis has been the most strongly associated risk factor. We report 8 cases of end stage kidney disease and renal adenocarcinoma. Median duration of hemodialysis was approximately 1 year, and 3 patients never had hemodialysis. Factors other than duration of dialysis, such as toxic metabolites, toxins from dialysis tubing, polyamines or other carcinogens, may be as or more important.
终末期肾病与囊性退变及肾腺癌之间的关联最早于1977年被认识到。自那时起，许多报告证实了这种关系。透析时间一直是最密切相关的危险因素。我们报告了8例终末期肾病合并肾腺癌的病例。血液透析的中位时间约为1年，3例患者从未进行过血液透析。除透析时间外的其他因素，如毒性代谢产物、透析管路中的毒素、多胺或其他致癌物，可能同样重要或更重要。
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