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海洛因注射部位坏死病例报告：尼科劳综合征的一种新的前驱症状

Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome.

作者信息

Rose Brandon, Powell Thomas G, Jones Michelle, Chillag Shawn A, Kemper Suzanne

机构信息

Internal Medicine, Baptist Health Medical Group, Kentucky, USA.

Transitional Year, Conway Medical Center, Conway, USA.

出版信息

Cureus. 2022 Sep 16;14(9):e29235. doi: 10.7759/cureus.29235. eCollection 2022 Sep.

DOI:10.7759/cureus.29235
PMID:36258944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9573776/
Abstract

Heroin injection-site necrosis (HISN) is a novel and poorly understood complication of intravenous drug abuse (IVDA). We present three cases of HISN that were evaluated and treated in Charleston, West Virginia, in 2019 and 2020. The documented cases show similarities involving patient care, follow-up, clinical progression, patient demographic, and dermatologic sequelae. We discuss these similarities, provide clinical recommendations, review proposed etiologies of HISN, and introduce Nicolau syndrome as a potential mechanism.

摘要

海洛因注射部位坏死（HISN）是静脉药物滥用（IVDA）一种新出现且了解甚少的并发症。我们介绍2019年和2020年在西弗吉尼亚州查尔斯顿市评估和治疗的3例HISN病例。记录在案的病例在患者护理、随访、临床进展、患者人口统计学特征和皮肤后遗症方面表现出相似之处。我们讨论这些相似之处，提供临床建议，回顾HISN的病因假说，并引入尼科劳综合征作为一种潜在机制。

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Case Reports of Heroin Injection Site Necrosis: A Novel Antecedent of Nicolau Syndrome.
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