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Pharmacogenomics in the era of personalised medicine.

作者信息

White Cassandra, Scott Rodney, Paul Christine L, Ackland Stephen P

机构信息

Maitland Hospital, Maitland, NSW.

University of Newcastle, Newcastle, NSW.

出版信息

Med J Aust. 2022 Nov 21;217(10):510-513. doi: 10.5694/mja2.51759. Epub 2022 Oct 18.

DOI:10.5694/mja2.51759
PMID:36259142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9827847/
Abstract
摘要

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本文引用的文献

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Clinical Implementation of Pharmacogenetic Testing to Prevent Early-Onset Fluoropyrimidine-Related Toxicity in Cancer Patients in Switzerland.瑞士癌症患者中预防早发性氟嘧啶相关毒性的药物遗传学检测的临床应用
Front Pharmacol. 2022 May 18;13:885259. doi: 10.3389/fphar.2022.885259. eCollection 2022.
2
Dihydropyrimidine Dehydrogenase Deficiency and Implementation of Upfront DPYD Genotyping.二氢嘧啶脱氢酶缺陷与前瞻性 DPYD 基因分型的实施。
Clin Pharmacol Ther. 2022 Oct;112(4):791-802. doi: 10.1002/cpt.2667. Epub 2022 Jun 12.
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Ethnic Diversity of DPD Activity and the Gene: Review of the Literature.二氢嘧啶脱氢酶活性及基因的种族多样性：文献综述
Pharmgenomics Pers Med. 2021 Dec 9;14:1603-1617. doi: 10.2147/PGPM.S337147. eCollection 2021.
4
Fluoropyrimidine chemotherapy: recommendations for DPYD genotyping and therapeutic drug monitoring of the Swiss Group of Pharmacogenomics and Personalised Therapy.氟嘧啶类化疗：瑞士药物基因组学和个体化治疗小组的 DPYD 基因分型和治疗药物监测建议。
Swiss Med Wkly. 2020 Nov 24;150:w20375. doi: 10.4414/smw.2020.20375. eCollection 2020 Nov 16.
5
DPD Testing Before Treatment With Fluoropyrimidines in the Amsterdam UMCs: An Evaluation of Current Pharmacogenetic Practice.阿姆斯特丹大学医学中心在使用氟嘧啶治疗前进行二氢嘧啶脱氢酶（DPD）检测：当前药物遗传学实践的评估
Front Pharmacol. 2020 Jan 28;10:1609. doi: 10.3389/fphar.2019.01609. eCollection 2019.
6
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction of DPYD and fluoropyrimidines.荷兰药物遗传学工作组（DPWG）关于 DPYD 和氟嘧啶类药物基因-药物相互作用的指南。
Eur J Hum Genet. 2020 Apr;28(4):508-517. doi: 10.1038/s41431-019-0540-0. Epub 2019 Nov 19.
7
Pharmacogenomics in general practice: The time has come.一般实践中的药物基因组学：时机已到。
Aust J Gen Pract. 2019 Mar;48(3):100-105. doi: 10.31128/AJGP-10-18-4733.
8
A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy.氟嘧啶类抗肿瘤治疗中 upfront DPYD 基因型指导剂量个体化的成本分析。
Eur J Cancer. 2019 Jan;107:60-67. doi: 10.1016/j.ejca.2018.11.010. Epub 2018 Dec 11.
9
Effectiveness and safety of reduced-dose fluoropyrimidine therapy in patients carrying the DPYD*2A variant: A matched pair analysis.携带 DPYD*2A 变异的患者中低剂量氟嘧啶治疗的有效性和安全性：一项配对分析。
Int J Cancer. 2019 May 1;144(9):2347-2354. doi: 10.1002/ijc.32022. Epub 2019 Jan 4.
10
DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis.基于 DPYD 基因型的氟嘧啶类药物个体化剂量在癌症患者中的应用：一项前瞻性安全性分析。
Lancet Oncol. 2018 Nov;19(11):1459-1467. doi: 10.1016/S1470-2045(18)30686-7. Epub 2018 Oct 19.