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退行性腰椎管狭窄症中动态与刚性内固定的临床及影像学结果比较

Comparison of clinical and radiological results of dynamic and rigid instrumentation in degenerative lumbar spinal stenosis.

作者信息

Varol Eyup, Etli Mustafa Umut, Avci Furkan, Yaltirik Cumhur Kaan, Ramazanoglu Ali Fatih, Onen Mehmet Resid, Naderi Sait

机构信息

Department of Neurosurgery, Ümraniye Training and Research Hospital, Health Sciences University, Istanbul, Turkey.

Department of Neurosurgery, VM Medical Park Maltepe Hospital, Istanbul, Turkey.

出版信息

J Craniovertebr Junction Spine. 2022 Jul-Sep;13(3):350-356. doi: 10.4103/jcvjs.jcvjs_63_22. Epub 2022 Sep 14.

DOI:10.4103/jcvjs.jcvjs_63_22
PMID:36263334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9574106/
Abstract

OBJECTIVE

Lumbar spinal stenosis is defined as a clinical syndrome characterized by neurogenic claudication or radicular pain due to the narrowing of the spinal canal or neural foramen and the compression of its neural elements. Surgical treatment is applied to decompress the neural structures. In some cases, transpedicular instrumentation and fusion may also be applied. In this study, we aimed to investigate and compare the preoperative and postoperative, clinical and radiological aspects of patients with lumbar spinal stenosis who underwent lumbar instrumentation using a polyetheretherketone (PEEK) rod or a titanium rod.

MATERIALS AND METHODS

In this study, the files of 293 patients who underwent posterior lumbar transpedicular stabilization between January 2015 and February 2018 in the Neurosurgery Clinic of Ümraniye Training and Research Hospital were reviewed retrospectively. Patients who did not meet the study criteria were excluded, and 127 patients who met the criteria and underwent posterior lumbar transpedicular stabilization due to lumbar spinal stenosis and/or lumbar degenerative disc disease were retrospectively reviewed. The patients were divided into two groups, dynamic and rigid, according to the rod types used. The two groups were compared using various postoperative clinical and radiological parameters.

RESULTS

The demographic data, surgical data, Visual Analog Scale-Oswestry Disability Index (VAS-ODI) data, and radiological data of both groups were carefully examined. There were 63 patients in the rigid group and 64 patients in the dynamic group. The age range in both groups was from 30 to 78 years, with a mean age of 56.44 years; 99 of the cases were female and 28 were male. The analysis of the participants' demographic data showed no significant differences between the two groups. Compared with the preoperative data, the postoperative evaluations revealed a significant decrease in VAS and ODI, but no significant difference was observed between the two groups. There was no difference between the two groups in terms of duration of surgery, follow-up time, operating distances, hospitalization duration, pseudoarthrosis, or fusion. Regarding the total and segmental range of motion, the affection was less in the dynamic group, which allowed for more movement. While there was no difference in disc height index between the two preoperative groups, it was observed that it was better maintained in the rigid group in the postoperative long term. Regarding foraminal height (FH), there was no difference between the two groups in the preoperative and early postoperative periods, but in the long term, FH was better maintained in the dynamic group. The long-term follow-ups revealed that adjacent segment disease (ASD) had developed in 19 patients in the rigid group, whereas ASD developed in only nine patients in the dynamic group. Based on these results, the probability of developing significant ASD in the rigid group was higher.

CONCLUSION

Previous experience with PEEK rod systems has demonstrated physiological spine movement, increased fusion rates, minimal complications, reduction in adjacent segment degeneration, and biomechanical compatibility. Although further long-term studies are needed and the cost of PEEK systems is likely to be a barrier, the results of the present study support the use of PEEK rods and other dynamic systems in spinal surgery.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144e/9574106/21502b3b4ee8/JCVJS-13-350-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144e/9574106/892585980f45/JCVJS-13-350-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144e/9574106/b95962fea878/JCVJS-13-350-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144e/9574106/21502b3b4ee8/JCVJS-13-350-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144e/9574106/892585980f45/JCVJS-13-350-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144e/9574106/b95962fea878/JCVJS-13-350-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144e/9574106/21502b3b4ee8/JCVJS-13-350-g003.jpg
摘要

目的

腰椎管狭窄症被定义为一种临床综合征,其特征为由于椎管或神经孔狭窄以及神经组织受压而导致神经源性间歇性跛行或神经根性疼痛。手术治疗旨在对神经结构进行减压。在某些情况下,还可能应用经椎弓根器械固定和融合术。在本研究中,我们旨在调查和比较接受聚醚醚酮(PEEK)棒或钛棒腰椎器械固定的腰椎管狭窄症患者术前和术后的临床及影像学情况。

材料与方法

在本研究中,回顾性分析了2015年1月至2018年2月在于尔勒尼耶培训与研究医院神经外科诊所接受后路腰椎椎弓根固定术的293例患者的病历。排除不符合研究标准的患者,对127例因腰椎管狭窄症和/或腰椎退行性椎间盘疾病符合标准并接受后路腰椎椎弓根固定术的患者进行回顾性分析。根据所使用的棒的类型,将患者分为动态组和刚性组。使用各种术后临床和影像学参数对两组进行比较。

结果

仔细检查了两组的人口统计学数据、手术数据、视觉模拟量表-奥斯威斯利残疾指数(VAS-ODI)数据和影像学数据。刚性组有63例患者,动态组有64例患者。两组的年龄范围均为30至78岁,平均年龄为56.44岁;其中99例为女性,28例为男性。对参与者人口统计学数据的分析显示两组之间无显著差异。与术前数据相比,术后评估显示VAS和ODI显著降低,但两组之间未观察到显著差异。两组在手术时间、随访时间、手术距离、住院时间、假关节形成或融合方面无差异。关于总活动度和节段活动度,动态组的影响较小,允许更多的活动。虽然术前两组之间的椎间盘高度指数无差异,但观察到在术后长期刚性组中该指数保持得更好。关于椎间孔高度(FH),术前和术后早期两组之间无差异,但从长期来看,动态组的FH保持得更好。长期随访显示,刚性组有19例患者发生了相邻节段疾病(ASD),而动态组仅有9例患者发生了ASD。基于这些结果,刚性组发生显著ASD的可能性更高。

结论

先前使用PEEK棒系统的经验表明其具有生理性脊柱运动、提高融合率、并发症最少、减少相邻节段退变以及生物力学兼容性。尽管需要进一步的长期研究,且PEEK系统的成本可能是一个障碍,但本研究结果支持在脊柱手术中使用PEEK棒和其他动态系统。

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