Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
J Cell Biol. 2022 Nov 7;221(11). doi: 10.1083/jcb.202210008. Epub 2022 Oct 20.
Lipid droplets (LDs) are key organelles for fat storage and trafficking. In this issue, Rogers et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202205053) show that glucose restriction triggers liquid crystalline lattice formation within LDs, which in turn alters the recruitment of proteins to the LD surface.
脂滴(LDs)是脂肪储存和运输的关键细胞器。在本期杂志中,Rogers 等人(2022. J. Cell Biol.https://doi.org/10.1083/jcb.202205053)表明,葡萄糖限制会触发 LDs 内液晶晶格的形成,进而改变蛋白质在 LD 表面的募集。