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脂滴进入细胞核。

Lipid droplets go nuclear.

作者信息

Farese Robert V, Walther Tobias C

机构信息

Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115 Department of Cell Biology, Harvard Medical School, Harvard University, Boston, MA 02115 Broad Institute of MIT and Harvard, Cambridge, MA 02142

Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115 Department of Cell Biology, Harvard Medical School, Harvard University, Boston, MA 02115 Howard Hughes Medical Institute, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115 Broad Institute of MIT and Harvard, Cambridge, MA 02142

出版信息

J Cell Biol. 2016 Jan 4;212(1):7-8. doi: 10.1083/jcb.201512056.

DOI:10.1083/jcb.201512056
PMID:26728852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4700486/
Abstract

Lipid droplets (LDs) are sometimes found in the nucleus of some cells. In this issue, Ohsaki et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507122) show that the nuclear membrane, promyelocytic leukemia bodies, and the protein PML-II play a role in nuclear LD formation, suggesting functional relationships between these structures.

摘要

脂滴(LDs)有时会在某些细胞的细胞核中被发现。在本期杂志中,大崎等人(2016年。《细胞生物学杂志》。http://dx.doi.org/10.1083/jcb.201507122)表明,核膜、早幼粒细胞白血病小体和蛋白质PML-II在细胞核脂滴形成过程中发挥作用,这表明这些结构之间存在功能关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02d0/4700486/77c01aed35de/JCB_201512056_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02d0/4700486/77c01aed35de/JCB_201512056_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02d0/4700486/77c01aed35de/JCB_201512056_Fig1.jpg

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J Cell Biol. 2016 Jan 4;212(1):29-38. doi: 10.1083/jcb.201507122.
2
The lipid droplet-a well-connected organelle.脂滴——一个联系紧密的细胞器。
Front Cell Dev Biol. 2015 Aug 12;3:49. doi: 10.3389/fcell.2015.00049. eCollection 2015.
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Lipid droplet biogenesis.脂滴的生物发生。
胆固醇是 BASP1 转录抑制所必需的。
Proc Natl Acad Sci U S A. 2021 Jul 20;118(29). doi: 10.1073/pnas.2101671118.
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A Novel Photosensitizer for Lipid Droplet-Location Photodynamic Therapy.一种用于脂滴定位光动力疗法的新型光敏剂。
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Nuclear lipid droplets and nuclear damage in Caenorhabditis elegans.线虫中的核脂质滴和核损伤。
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