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新冠感染 1 年后的认知功能障碍:来自眼动追踪的证据。

Cognitive dysfunction 1 year after COVID-19: evidence from eye tracking.

机构信息

Department of Neurology, Medical University of Innsbruck, 6020, Innsbruck, Austria.

Interactive Graphics and Simulation Group, University of Innsbruck, 6020, Innsbruck, Austria.

出版信息

Ann Clin Transl Neurol. 2022 Nov;9(11):1826-1831. doi: 10.1002/acn3.51675. Epub 2022 Oct 20.

Abstract

Increasing evidence suggests persistent cognitive dysfunction after COVID-19. In this cross-sectional study, frontal lobe function was assessed 12 months after the acute phase of the disease, using tailored eye tracking assessments. Individuals who recovered from COVID-19 made significantly more errors in all eye tracking tasks compared to age/sex-matched healthy controls. Furthermore, patients who were treated as inpatients performed worse compared to outpatients and controls. Our results show impaired inhibitory cortical control in individuals who recovered from COVID-19. The association between disease severity and its sequelae may contribute to a better understanding of post-COVID-19 cognitive function.

摘要

越来越多的证据表明,新冠病毒感染后会持续存在认知功能障碍。在这项横断面研究中,使用定制的眼动追踪评估,在疾病急性期后 12 个月评估额叶功能。与年龄/性别匹配的健康对照组相比,从 COVID-19 中康复的个体在所有眼动追踪任务中明显犯了更多的错误。此外,与门诊患者和对照组相比,住院治疗的患者表现更差。我们的研究结果表明,从 COVID-19 中康复的个体存在抑制性皮质控制受损。疾病严重程度及其后遗症之间的关联可能有助于更好地理解新冠感染后的认知功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07c5/9639623/21cb591737f9/ACN3-9-1826-g001.jpg

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