Haddad Isabelle, Kozman Kathia, Kibbi Abdul-Ghani
Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.
Front Allergy. 2022 Oct 4;3:809646. doi: 10.3389/falgy.2022.809646. eCollection 2022.
A rapid spread of different strains of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an unprecedented pandemic. Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, the medical body has encountered major obstacles concerning disease management at different levels. Even though patients infected with this virus mainly present with respiratory symptoms, it has been associated with a plethora of well-documented cutaneous manifestations in the literature. However, little investigations have been conducted concerning COVID-19 and its impact on skin disorders mediated by type 2 inflammation leaving multiple dermatologists and other specialists perplexed by the lack of clinical guidelines or pathways. This review focuses on the effects of this pandemic in patients with skin disorders mediated by type 2 inflammation, specifically atopic dermatitis and chronic spontaneous urticaria. In addition, it will provide clinicians a guide on treatment and vaccination considerations for this stated set of patients.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)不同毒株的迅速传播导致了一场前所未有的大流行。自2019冠状病毒病(COVID-19)大流行开始以来,医疗界在不同层面的疾病管理方面遇到了重大障碍。尽管感染这种病毒的患者主要表现出呼吸道症状,但文献中已有大量关于其皮肤表现的记载。然而,关于COVID-19及其对2型炎症介导的皮肤疾病的影响的研究很少,这使得许多皮肤科医生和其他专科医生因缺乏临床指南或路径而感到困惑。本综述重点关注这场大流行对2型炎症介导的皮肤疾病患者的影响,特别是特应性皮炎和慢性自发性荨麻疹。此外,它将为临床医生提供针对这组特定患者的治疗和疫苗接种考虑的指南。