• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

椎体脆性骨折患者疼痛控制的药物治疗选择

Pharmacological options for pain control in patients with vertebral fragility fractures.

作者信息

Tanna Nuttan Kantilal, Ong Terence

机构信息

Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom.

Department of Medicine, Faculty of Medicine, University Malaya, 50603, Kuala Lumpur, Malaysia.

出版信息

Osteoporos Sarcopenia. 2022 Sep;8(3):93-97. doi: 10.1016/j.afos.2022.09.003. Epub 2022 Oct 3.

DOI:10.1016/j.afos.2022.09.003
PMID:36268497
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9577215/
Abstract

This review considers the evidence base and current knowledge for pharmacological treatment options that are available for pain control in patients with vertebral fractures sustained after a low trauma incident. Due care needs to be taken when considering prescribed options for pain control. The decision should be based on first establishing whether the presentation is one of acute severe pain at the time of a new vertebral fragility fracture incident or whether the complaint is one of the debilitating, longer term chronic back pain syndrome, accompanied by a clinical suspicion of a possible new fracture. The article also presents currently debated questions in this important area of clinical and patient care and will be of interest to the readership worldwide.

摘要

本综述探讨了低创伤事件后发生椎体骨折的患者疼痛控制可用药物治疗方案的证据基础和当前知识。在考虑规定的疼痛控制方案时需要格外谨慎。该决定应首先基于确定症状是新的椎体脆性骨折事件时的急性剧痛,还是伴有可能新发骨折临床怀疑的衰弱性长期慢性背痛综合征。本文还提出了这一临床和患者护理重要领域当前存在争议的问题,全球读者可能会感兴趣。

相似文献

1
Pharmacological options for pain control in patients with vertebral fragility fractures.椎体脆性骨折患者疼痛控制的药物治疗选择
Osteoporos Sarcopenia. 2022 Sep;8(3):93-97. doi: 10.1016/j.afos.2022.09.003. Epub 2022 Oct 3.
2
Rates of osteoporosis screening and treatment following vertebral fracture.椎体骨折后骨质疏松症的筛查和治疗率。
Spine J. 2019 Mar;19(3):411-417. doi: 10.1016/j.spinee.2018.08.004. Epub 2018 Aug 22.
3
Back pain in osteoporotic vertebral fractures.骨质疏松性椎体骨折中的背痛
Osteoporos Int. 2008 Jul;19(7):895-903. doi: 10.1007/s00198-007-0530-x. Epub 2007 Dec 11.
4
Low-dose diclofenac in patients with fragility fractures.低剂量双氯芬酸用于脆性骨折患者
Clin Cases Miner Bone Metab. 2017 Jan-Apr;14(1):15-17. doi: 10.11138/ccmbm/2017.14.1.015. Epub 2017 May 30.
5
The management of patients admitted to hospital with vertebral fragility fractures: experience from a UK university hospital.英国某大学附属医院收治的椎体脆弱性骨折患者的管理:经验总结。
Injury. 2021 Oct;52(10):2903-2907. doi: 10.1016/j.injury.2021.06.028. Epub 2021 Jul 2.
6
7
Underdiagnosis of osteoporotic vertebral fractures in patients with fragility fractures: retrospective analysis of over 300 patients.脆性骨折患者骨质疏松性椎体骨折的漏诊情况:对300余例患者的回顾性分析
Clin Cases Miner Bone Metab. 2016 May-Aug;13(2):119-122. doi: 10.11138/ccmbm/2016.13.2.119. Epub 2016 Oct 5.
8
Management of glucocorticoid-related osteoporotic vertebral fracture.糖皮质激素相关骨质疏松性椎体骨折的管理
Osteoporos Sarcopenia. 2020 Mar;6(1):1-7. doi: 10.1016/j.afos.2020.02.002. Epub 2020 Mar 3.
9
Comparison of the Characteristics of Back Pain in Women with Postmenopausal Osteoporosis with and without Vertebral Compression Fracture: A Retrospective Study at a Single Osteoporosis Center in Poland.比较波兰单一骨质疏松症中心绝经后骨质疏松症伴与不伴椎体压缩性骨折女性背痛特征的回顾性研究。
Med Sci Monit. 2021 Feb 18;27:e929853. doi: 10.12659/MSM.929853.
10
Vertebral Fragility Fractures (VFF)-Who, when and how to operate.椎体脆性骨折(VFF)——哪些人、何时以及如何进行手术。
Injury. 2018 Aug;49(8):1430-1435. doi: 10.1016/j.injury.2018.04.018. Epub 2018 Apr 22.

引用本文的文献

1
Challenges of Treating a C2 Odontoid Fracture in an Elderly Patient With Multiple Comorbidities: A Case Report.治疗一名患有多种合并症的老年患者 C2 齿状突骨折的挑战:病例报告
Cureus. 2024 Dec 6;16(12):e75242. doi: 10.7759/cureus.75242. eCollection 2024 Dec.
2
Biochemical Mechanisms and Rehabilitation Strategies in Osteoporosis-Related Pain: A Systematic Review.骨质疏松症相关性疼痛的生化机制及康复策略:一项系统综述
Clin Pract. 2024 Dec 19;14(6):2737-2758. doi: 10.3390/clinpract14060216.
3
Characteristics and outcomes of inpatients aged 85 and older with thoracolumbar vertebral fractures: impact on hospital stay and mortality.

本文引用的文献

1
SCOPE 2021: a new scorecard for osteoporosis in Europe.《2021年欧洲骨质疏松症评分指南》:欧洲骨质疏松症的新记分卡
Arch Osteoporos. 2021 Jun 2;16(1):82. doi: 10.1007/s11657-020-00871-9.
2
The efficacy of teriparatide on lumbar spine bone mineral density, vertebral fracture incidence and pain in post-menopausal osteoporotic patients: A systematic review and meta-analysis.特立帕肽对绝经后骨质疏松症患者腰椎骨密度、椎体骨折发生率及疼痛的疗效:一项系统评价与Meta分析
Bone Rep. 2020 Oct 16;13:100728. doi: 10.1016/j.bonr.2020.100728. eCollection 2020 Dec.
3
Effect of Preoperative Zoledronic Acid Administration on Pain Intensity after Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures.
85 岁及以上胸腰椎骨折住院患者的特征和结局:对住院时间和死亡率的影响。
Eur Spine J. 2024 Dec;33(12):4504-4512. doi: 10.1007/s00586-024-08520-2. Epub 2024 Oct 22.
4
Pain Management in Osteoporosis.骨质疏松症的疼痛管理
Indian J Orthop. 2023 Nov 21;57(Suppl 1):230-236. doi: 10.1007/s43465-023-01047-6. eCollection 2023 Dec.
唑来膦酸术前给药对骨质疏松性椎体压缩骨折经皮椎体成形术后疼痛强度的影响。
Pain Res Manag. 2020 Aug 3;2020:8039671. doi: 10.1155/2020/8039671. eCollection 2020.
4
Vertebral Compression Fractures: Evaluation and Management.椎体压缩性骨折:评估与处理
Semin Intervent Radiol. 2020 Jun;37(2):214-219. doi: 10.1055/s-0040-1709208. Epub 2020 May 14.
5
Current Concepts in the Management of Vertebral Compression Fractures.当前椎体压缩性骨折治疗的理念。
Curr Pain Headache Rep. 2020 Mar 20;24(5):16. doi: 10.1007/s11916-020-00849-9.
6
Effect of Osteoporosis Medication on Fracture Healing: An Evidence Based Review.骨质疏松症药物对骨折愈合的影响:一项基于证据的综述。
J Bone Metab. 2020 Feb;27(1):15-26. doi: 10.11005/jbm.2020.27.1.15. Epub 2020 Feb 29.
7
Efficacy of calcitonin for treating acute pain associated with osteoporotic vertebral compression fracture: an updated systematic review.降钙素治疗骨质疏松性椎体压缩性骨折相关急性疼痛的疗效:一项更新的系统评价。
CJEM. 2020 May;22(3):359-367. doi: 10.1017/cem.2019.490.
8
Bone Pain in Cancer Patients: Mechanisms and Current Treatment.癌症患者的骨痛:机制与现行治疗。
Int J Mol Sci. 2019 Nov 30;20(23):6047. doi: 10.3390/ijms20236047.
9
The Nottingham Spinal Health (NoSH) Study: a cohort study of patients hospitalised with vertebral fragility fractures.诺丁汉脊柱健康(NoSH)研究:一项与椎体脆性骨折住院患者相关的队列研究。
Osteoporos Int. 2020 Feb;31(2):363-370. doi: 10.1007/s00198-019-05198-x. Epub 2019 Nov 6.
10
12-Month Teriparatide Treatment Reduces New Vertebral Compression Fractures Incidence And Back Pain And Improves Quality Of Life After Percutaneous Kyphoplasty In Osteoporotic Women.特立帕肽治疗 12 个月可降低骨质疏松症女性行经皮椎体后凸成形术后新发椎体压缩性骨折发生率和背痛发生率,并改善生活质量。
Clin Interv Aging. 2019 Oct 1;14:1693-1703. doi: 10.2147/CIA.S224663. eCollection 2019.