• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Highly sensitive genotyping of MTHFR C677T polymorphisms using a novel RPA-LDR-qPCR assay.

作者信息

Si Xinxin, Gu Qinghua, Zhao Chenjie, Zhang Xiao, Xiao Tingting, Li Yu, Ying Wei, Gao Song

机构信息

Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Co-Innovation Center of Jiangsu Marine Bio-industry Technology, School of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China.

Department of Pathology, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China.

出版信息

Acta Biochim Biophys Sin (Shanghai). 2022 Oct 25;54(11):1753-1756. doi: 10.3724/abbs.2022151.

DOI:10.3724/abbs.2022151
PMID:36269136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9828550/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eb9/9828550/ad2ff6be4d62/abbs-2022-095-t1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eb9/9828550/ad2ff6be4d62/abbs-2022-095-t1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4eb9/9828550/ad2ff6be4d62/abbs-2022-095-t1.jpg

相似文献

1
Highly sensitive genotyping of MTHFR C677T polymorphisms using a novel RPA-LDR-qPCR assay.使用新型RPA-LDR-qPCR分析法对亚甲基四氢叶酸还原酶（MTHFR）C677T多态性进行高灵敏度基因分型。
Acta Biochim Biophys Sin (Shanghai). 2022 Oct 25;54(11):1753-1756. doi: 10.3724/abbs.2022151.
2
Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population.沙特人群中亚甲基四氢叶酸还原酶（MTHFR）C677T多态性与原发性青光眼的关联
BMC Ophthalmol. 2016 Sep 1;16(1):156. doi: 10.1186/s12886-016-0337-7.
3
Methylenetetrahydrofolate reductase (MTHFR) gene C677T, A1298C and G1793A polymorphisms: association with risk for clear cell renal cell carcinoma and tumour behaviour in men.亚甲基四氢叶酸还原酶（MTHFR）基因 C677T、A1298C 和 G1793A 多态性：与男性透明细胞肾细胞癌风险和肿瘤行为的关联。
Clin Oncol (R Coll Radiol). 2012 May;24(4):269-81. doi: 10.1016/j.clon.2011.03.005. Epub 2011 Apr 13.
4
The MTHFR C677T Polymorphism and Risk of Intracerebral Hemorrhage in a Chinese Han Population.中国汉族人群中MTHFR基因C677T多态性与脑出血风险
Med Sci Monit. 2016 Jan 12;22:127-33. doi: 10.12659/msm.896315.
5
Role of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in polycystic ovary syndrome risk.亚甲基四氢叶酸还原酶C677T和A1298C基因多态性在多囊卵巢综合征风险中的作用。
Genet Mol Res. 2016 Dec 23;15(4):gmr-15-04-gmr.15048570. doi: 10.4238/gmr15048570.
6
Association Analysis of Methylenetetrahydrofolate Reductase Common Gene Polymorphisms with Breast Cancer Risk in an Iranian Population: A Case-Control Study and a Stratified Analysis.亚甲基四氢叶酸还原酶常见基因多态性与伊朗人群乳腺癌风险的关联分析：病例对照研究和分层分析。
Asian Pac J Cancer Prev. 2020 Sep 1;21(9):2709-2714. doi: 10.31557/APJCP.2020.21.9.2709.
7
Prevalence of MTHFR gene polymorphisms (C677T and A1298C) among Tamilians.泰米尔人中MTHFR基因多态性（C677T和A1298C）的患病率。
Exp Mol Pathol. 2004 Oct;77(2):85-8. doi: 10.1016/j.yexmp.2004.04.006.
8
Polymorphisms in methylenetetrahydrofolate reductase and cystathionine beta-synthase in oral cancer - a case-control study in southeastern Brazilians.口腔癌中甲基四氢叶酸还原酶和胱硫醚β-合酶的多态性——巴西东南部的一项病例对照研究
Braz J Otorhinolaryngol. 2016 Sep-Oct;82(5):558-66. doi: 10.1016/j.bjorl.2015.10.012. Epub 2015 Dec 17.
9
MTHFR gene polymorphisms in bladder cancer in the Turkish population.土耳其人群膀胱癌中的亚甲基四氢叶酸还原酶（MTHFR）基因多态性
Asian Pac J Cancer Prev. 2011;12(7):1833-5.
10
Association of Methylenetetrahydrofolate Reductase C677T and A1298C Gene Polymorphisms With Recurrent Pregnancy Loss in Syrian Women.亚甲基四氢叶酸还原酶 C677T 和 A1298C 基因多态性与叙利亚妇女复发性流产的关系。
Reprod Sci. 2017 Sep;24(9):1275-1279. doi: 10.1177/1933719116682874. Epub 2016 Dec 21.

本文引用的文献

1
An isothermal recombinase polymerase amplification and lateral flow strip combined method for rapid on-site detection of Vibrio vulnificus in raw seafood.等温重组酶聚合酶扩增与侧向流条带相结合的方法快速现场检测生海鲜中的创伤弧菌。
Food Microbiol. 2021 Sep;98:103664. doi: 10.1016/j.fm.2020.103664. Epub 2020 Oct 15.
2
Single probe PCR melting curve analysis MTHFR C677T SNP sites.单探针聚合酶链反应熔解曲线分析 MTHFR C677T SNP 位点。
Anal Biochem. 2021 Apr 15;619:114102. doi: 10.1016/j.ab.2021.114102. Epub 2021 Jan 13.
3
All-in-one approaches for rapid and highly specific quantifcation of single nucleotide polymorphisms based on ligase detection reaction using molecular beacons as turn-on probes.
基于分子信标作为开启探针的连接酶检测反应的用于快速且高度特异性单核苷酸多态性定量的一体化方法。
Talanta. 2021 Mar 1;224:121717. doi: 10.1016/j.talanta.2020.121717. Epub 2020 Oct 31.
4
Single-molecule detection of cancer mutations using a novel PCR-LDR-qPCR assay.利用新型 PCR-LDR-qPCR 检测方法进行癌症基因突变的单分子检测。
Hum Mutat. 2020 May;41(5):1051-1068. doi: 10.1002/humu.23987. Epub 2020 Feb 17.
5
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: epidemiology, metabolism and the associated diseases.亚甲基四氢叶酸还原酶（MTHFR）C677T多态性：流行病学、代谢及相关疾病
Eur J Med Genet. 2015 Jan;58(1):1-10. doi: 10.1016/j.ejmg.2014.10.004. Epub 2014 Nov 4.
6
Folate: metabolism, genes, polymorphisms and the associated diseases.叶酸：代谢、基因、多态性及相关疾病。
Gene. 2014 Jan 1;533(1):11-20. doi: 10.1016/j.gene.2013.09.063. Epub 2013 Oct 1.
7
The TaqMan method for SNP genotyping.用于单核苷酸多态性基因分型的TaqMan方法。
Methods Mol Biol. 2009;578:293-306. doi: 10.1007/978-1-60327-411-1_19.
8
DNA detection using recombination proteins.使用重组蛋白进行DNA检测。
PLoS Biol. 2006 Jul;4(7):e204. doi: 10.1371/journal.pbio.0040204.
9
Polymerase chain reaction/ligase detection reaction/hybridization assays using flow-through microfluidic devices for the detection of low-abundant DNA point mutations.使用流通式微流控装置进行聚合酶链反应/连接酶检测反应/杂交分析以检测低丰度DNA点突变
Biosens Bioelectron. 2006 Apr 15;21(10):1915-23. doi: 10.1016/j.bios.2006.01.014. Epub 2006 Feb 20.
10
A method for homogeneous color-compensated genotyping of factor V (G1691A) and methylenetetrahydrofolate reductase (C677T) mutations using real-time multiplex fluorescence PCR.
Clin Biochem. 2000 Oct;33(7):535-9. doi: 10.1016/s0009-9120(00)00161-2.