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冷冻疗法治疗副气管支气管阻塞性乳头状瘤:病例报告。

Use of cryotherapy to treat obstructing papilloma of an accessory tracheal bronchus: case report.

机构信息

Department of Surgery, Morristown Medical Center, 100 Madison Ave, Morristown, NJ, 07960, USA.

Division of Cardiothoracic Surgery, Morristown Medical Center, 100 Madison Ave, Morristown, NJ, 07960, USA.

出版信息

J Cardiothorac Surg. 2022 Oct 22;17(1):273. doi: 10.1186/s13019-022-01977-6.

DOI:10.1186/s13019-022-01977-6
PMID:36273154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9588236/
Abstract

BACKGROUND

Tracheal papillomatosis is a relatively rare condition with limited data on successful treatment modalities. To our knowledge, this is the first report to describe a papilloma arising from an accessory bronchus. Furthermore, this case report demonstrates successful treatment with clinical and patient-centered improvements after use of Spray Cryotherapy.

CASE PRESENTATION

A 71-year-old woman presented with one year history of recurrent fevers and intermittent hemoptysis. Imaging and video bronchoscopy revealed an obstructing papilloma of an accessory tracheal bronchus to the right upper lobe. She was treated with debridement followed by multiple cryotherapy treatments resulting in complete clinical and radiographic resolution of her post-obstructive pneumonia.

CONCLUSIONS

This case report not only supports existing literature on the use of cryotherapy for airway diseases but also presents a unique form of obstructing papilloma confined to an accessory bronchus, the only report of its kind based on extensive literature review.

摘要

背景

气管乳头瘤病是一种相对罕见的疾病,关于成功治疗方式的数据有限。据我们所知,这是首例描述起源于副支气管的乳头瘤的报告。此外,本病例报告显示,使用喷雾冷冻疗法后,在临床和以患者为中心的方面都有了显著改善。

病例介绍

一名 71 岁女性因反复发热和间歇性咯血一年就诊。影像学和视频支气管镜检查显示右上叶一个辅助性气管支气管阻塞性乳头瘤。她接受了清创术,随后进行了多次冷冻治疗,导致阻塞性肺炎完全临床和放射学缓解。

结论

本病例报告不仅支持了冷冻疗法在气道疾病中的应用的现有文献,还提出了一种独特形式的阻塞性乳头瘤,局限于副支气管,这是基于广泛文献回顾的唯一此类报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54c6/9588236/3ec427dc7f6e/13019_2022_1977_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54c6/9588236/fd249d69ee1f/13019_2022_1977_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54c6/9588236/76caefd4786a/13019_2022_1977_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54c6/9588236/3ec427dc7f6e/13019_2022_1977_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54c6/9588236/fd249d69ee1f/13019_2022_1977_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54c6/9588236/76caefd4786a/13019_2022_1977_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54c6/9588236/3ec427dc7f6e/13019_2022_1977_Fig3_HTML.jpg

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本文引用的文献

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Biologics for the Treatment of Recurrent Respiratory Papillomatosis.生物制剂治疗复发性呼吸道乳头瘤病。
Otolaryngol Clin North Am. 2021 Aug;54(4):769-777. doi: 10.1016/j.otc.2021.05.002. Epub 2021 Jun 5.
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Recurrent respiratory papillomatosis: A 2020 perspective.复发性呼吸道乳头状瘤病:2020年视角
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Systemic Bevacizumab for Treatment of Respiratory Papillomatosis: International Consensus Statement.系统性贝伐珠单抗治疗呼吸道乳头瘤病:国际共识声明。
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Curing a Patient of Recurrent Tracheal Papillomatosis Using Laser Ablation and Adjuvant Radiotherapy.激光消融联合辅助放疗治愈复发性气管乳头状瘤病患者。
Ann Thorac Surg. 2020 Aug;110(2):e91-e93. doi: 10.1016/j.athoracsur.2019.12.043. Epub 2020 Feb 5.
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Systemic bevacizumab for recurrent respiratory papillomatosis: A national survey.用于复发性呼吸道乳头状瘤病的全身性贝伐单抗:一项全国性调查。
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