Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Centre for Anaesthesia, University Clinical Centre of Serbia, Belgrade, Serbia.
Med Princ Pract. 2022;31(6):570-577. doi: 10.1159/000527272. Epub 2022 Oct 21.
Thyroid dysfunction is a common cause of atrial fibrillation (AF). Incidence of AF is high in patients with both expressed and subclinical hyperthyroidism. The aim of our study was to determine the incidence and predictors of new onset atrial fibrillation (NOAF) in euthyroid patients undergoing thyroid surgery.
The study included 1,252 euthyroid patients with American Society of Anesthesiologists (ASA) physical status ASA 2 and ASA 3, who were 18 years and older and were in sinus rhythm. Patients without comorbidity and patients with persistent AF were excluded. We investigated the influence of the following preoperative characteristics on the occurrence of NOAF: age, sex, body mass index, ASA score, admission diagnoses, and comorbidity. We noted the influence of difficult intubation of trachea, type and duration of surgery, and time under general anaesthesia. Univariate and multivariate logistic regression were used to determine predictors of occurrence of NOAF.
NOAF was noted in 0.72% of patients. Patients with NOAF were older (63.11 vs. 56.81 years) than patients without NOAF, but this was not statistically significant. Significantly more patients from the NOAF group had preoperative heart rhythm disturbance and a history of angina pectoris, in contrast to patients without registered NOAF (p = 0.001; p = 0.017). Multivariate analysis showed that a history of heart rhythm disturbance was an independent predictor of NOAF.
Incidence of NOAF during thyroid surgery is similar to the other type of surgery, if the values of thyroid hormones are normal.
甲状腺功能障碍是心房颤动(AF)的常见原因。显性和亚临床甲状腺功能亢进症患者的 AF 发生率均较高。我们的研究旨在确定甲状腺功能正常的甲状腺手术患者新发心房颤动(NOAF)的发生率和预测因素。
该研究纳入了 1252 例美国麻醉医师协会(ASA)身体状况为 ASA 2 和 ASA 3 的甲状腺功能正常的成年患者(18 岁及以上),窦性心律。排除了合并症患者和持续性房颤患者。我们研究了以下术前特征对 NOAF 发生的影响:年龄、性别、体重指数、ASA 评分、入院诊断和合并症。我们注意到气管插管困难、手术类型和持续时间以及全身麻醉时间对 NOAF 发生的影响。使用单变量和多变量逻辑回归来确定 NOAF 发生的预测因素。
0.72%的患者出现了 NOAF。与无 NOAF 的患者相比,NOAF 患者的年龄更大(63.11 岁 vs. 56.81 岁),但无统计学意义。与未登记 NOAF 的患者相比,NOAF 组有更多的患者术前存在心律失常和心绞痛病史(p=0.001;p=0.017)。多变量分析显示,心律失常病史是 NOAF 的独立预测因素。
如果甲状腺激素值正常,甲状腺手术期间新发心房颤动的发生率与其他类型的手术相似。