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沙特阿拉伯初级保健中心老年人群维生素D缺乏症的临床鉴定

Clinical Identification of Hypovitaminosis D among Elderly Attending Primary Care Centre in Saudi Arabia.

作者信息

Alzahrani Abdullah M, Emam Leena S, Alsharif Maryam S, Hakami Alqassem Y, Aga Syed Sameer

机构信息

Department of Primary Health Care, Ministry of National Guard Health Affairs (MNGHA), King Abdulaziz Medical City, Jeddah, Saudi Arabia.

Research Office, King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard Health Affairs (MNGHA), King Abdulaziz Medical City, Jeddah, Saudi Arabia.

出版信息

Biochem Res Int. 2022 Oct 12;2022:6341645. doi: 10.1155/2022/6341645. eCollection 2022.

Abstract

BACKGROUND

A large proportion of elderly people suffer from hypovitaminosis D, and depending on the severity of the condition, they develop complications that are detrimental to their health.

OBJECTIVE

To determine the consistency between the results of the vitamin D level in the blood compared to the result with the score of a simple questionnaire (Physician Vitamin D Status Predictor - VDSP) for elderly patients. This is a cross-sectional study conducted during the period between October 2018 and November 2019 in 3 primary health care centres (PHCCs) in Jeddah, Saudi Arabia. The subjects for this study were patients aged 60 or older. Data were collected in two phases: a questionnaire approach as the first phase, while the second phase involved blood testing for vitamin D levels. The validated questionnaire used in this study was the Physician`s Vitamin D Status Predictor (VDSP).

RESULTS

The study included 335 participants who ranged between 60 and 107 years old with a mean age of 68.2 years and standard deviation (SD) of 7.3 years. Females represented 66.9% of the total participants. The prevalence of vitamin D deficiency was 60.8%; among them, 7.2% were categorized as severe deficiency, whereas the prevalence of vitamin D insufficiency was 29.9%. The outcomes of VDSP survey were not directly associated with serum 25(OH)D levels in elderly people, except for the number of medications. In addition, vitamin D supplementation was associated with serum 25(OH)D levels among those patients.

CONCLUSION

Vitamin D supplementation was significantly associated with serum 25(OH)D levels. Moreover, this study showed a significant association between serum 25(OH)D levels and the number of medications taken by the participants.

摘要

背景

很大一部分老年人患有维生素D缺乏症,根据病情严重程度,他们会出现对健康有害的并发症。

目的

确定老年患者血液中维生素D水平的检测结果与一份简单问卷(医生维生素D状态预测器 - VDSP)得分结果之间的一致性。这是一项横断面研究,于2018年10月至2019年11月期间在沙特阿拉伯吉达的3个初级卫生保健中心(PHCCs)进行。本研究的对象为60岁及以上的患者。数据收集分两个阶段进行:第一阶段采用问卷调查法,而第二阶段涉及检测血液中的维生素D水平。本研究中使用的经过验证的问卷是医生维生素D状态预测器(VDSP)。

结果

该研究纳入了335名参与者,年龄在60至107岁之间,平均年龄为68.2岁,标准差(SD)为7.3岁。女性占总参与者的66.9%。维生素D缺乏的患病率为60.8%;其中,7.2%被归类为严重缺乏,而维生素D不足的患病率为29.9%。除用药数量外,VDSP调查结果与老年人血清25(OH)D水平无直接关联。此外,在这些患者中,维生素D补充剂与血清25(OH)D水平相关。

结论

维生素D补充剂与血清25(OH)D水平显著相关。此外,本研究表明血清25(OH)D水平与参与者的用药数量之间存在显著关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2952/9581707/e9be22a941c5/BRI2022-6341645.001.jpg

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