Annweiler Cedric, Kabeshova Anastasiia, Callens Alix, Paty Marie-Liesse, Duval Guillaume T, Holick Michael F
Department of Neurosciences and Aging, Division of Geriatric Medicine, Angers University Hospital; Angers University Memory Clinic; Research Center on Autonomy and Longevity; UPRES EA 4638, University of Angers, UNAM, Angers, France.
Robarts Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, the University of Western Ontario, London, Ontario, Canada.
PLoS One. 2017 Nov 1;12(11):e0186578. doi: 10.1371/journal.pone.0186578. eCollection 2017.
The 16-item Vitamin D Status Predictor (VDSP) questionnaire helps to identify, without resorting to a blood test, older adults with low vitamin D concentrations. Our objective was to determine whether a self-administered VDSP was concordant with the VDSP administered by a physician, and to examine the concordance of every single item of the VDSP.
A total of 349 older in- and outpatients (mean, 83.2±7.2years; 59% female) were consecutively recruited in the geriatric ward of the University Hospital of Angers, France. All participants completed a self-administered VDSP questionnaire (self-VDSP) in paper format composed of 17 items exploring age, gender, general condition, nutrition, vision, mood, cognition, gait and falls, and osteoporosis. All participants underwent subsequently a full clinical examination by a physician exploring the same areas (rater-VDSP).
The agreement between the self-VDSP and the rater-VDSP was almost perfect for the probability of having low vitamin D concentrations, regardless of the definition used (i.e., ≤25, ≤50 or ≤75 nmol/L). The agreements between physicians' and patients' responses were significant for every single VDSP item. The agreement was fair to perfect for all items, except for cognitive disorders, undernutrition and polymorbidity (poor agreement).
Older adults are able to evaluate their own probabilities of severe vitamin D deficiency, deficiency and insufficiency. A self-questionnaire may promote the use of the VDSP tool in this population, and help clinicians in decisions to supplement their patients in a reasoned way.
16项维生素D状态预测问卷(VDSP)有助于在不进行血液检测的情况下识别维生素D浓度较低的老年人。我们的目的是确定自行填写的VDSP与医生填写的VDSP是否一致,并检查VDSP各项内容的一致性。
在法国昂热大学医院老年病房连续招募了349名老年住院患者和门诊患者(平均年龄83.2±7.2岁;女性占59%)。所有参与者均以纸质形式完成了一份自行填写的VDSP问卷(自我VDSP),该问卷包含17个项目,涉及年龄、性别、一般状况、营养、视力、情绪、认知、步态与跌倒以及骨质疏松症。随后,所有参与者均接受了医生针对相同领域的全面临床检查(评估者VDSP)。
无论采用何种定义(即≤25、≤50或≤75 nmol/L),自我VDSP与评估者VDSP在维生素D浓度较低可能性方面的一致性几乎完美。对于VDSP的每个单项,医生与患者的回答之间均存在显著一致性。除认知障碍、营养不良和多种疾病(一致性较差)外,所有项目的一致性为中等至完美。
老年人能够评估自身维生素D严重缺乏、缺乏和不足的可能性。自我问卷可能会促进VDSP工具在该人群中的使用,并帮助临床医生合理地决定是否为患者进行补充治疗。