School of Nursing, Jilin University, 965 Xinjiang Street, Changchun, Jilin 130000, China.
Comput Math Methods Med. 2022 Oct 12;2022:6771005. doi: 10.1155/2022/6771005. eCollection 2022.
The purpose of this study was to investigate the relationship among depression, alexithymia, and social support and examine the main influence factors of depression in patients with colorectal cancer (CRC). In addition, the mediating role of alexithymia between social support and depression was analyzed.
Patients with CRC were recruited in two tertiary hospitals in Changchun via a convenience sampling method. All survivors were asked to complete self-report questionnaires assessing medical and demographic variables, depression, alexithymia, and social support.
A total of 183 patients with CRC were included. The results showed that education level and family monthly income were the main factors affecting depression patients with in CRC. Alexithymia was positively correlated with depression ( = 0.389, < 0.01). Social support was negatively correlated with alexithymia ( = -0.322, < 0.01) and depression ( = -0.316, < 0.01). Moreover, alexithmia partially mediated the relationship between social support and depression, and the ratio of mediating effect with total effect was 23.82%.
To sum up, there is a correlation between depression, social support, and alexithymia in patients with CRC; alexithymia plays a partially intermediary role in the impact of social support on depression. Our findings remind clinicians to treat the depression of patients with CRC from multiple perspectives, such as by increasing social support and reducing alexithymia.
本研究旨在探讨抑郁、述情障碍和社会支持之间的关系,并考察结直肠癌(CRC)患者抑郁的主要影响因素。此外,还分析了述情障碍在社会支持与抑郁之间的中介作用。
采用便利抽样法,在长春的两家三级医院招募 CRC 患者。所有幸存者均被要求完成自我报告问卷,评估医疗和人口统计学变量、抑郁、述情障碍和社会支持。
共纳入 183 例 CRC 患者。结果表明,教育水平和家庭月收入是影响 CRC 患者抑郁的主要因素。述情障碍与抑郁呈正相关( = 0.389, < 0.01)。社会支持与述情障碍呈负相关( = -0.322, < 0.01),与抑郁呈负相关( = -0.316, < 0.01)。此外,述情障碍部分中介了社会支持与抑郁之间的关系,中介效应占总效应的 23.82%。
总之,CRC 患者的抑郁、社会支持和述情障碍之间存在相关性;述情障碍在社会支持对抑郁的影响中起部分中介作用。我们的研究结果提醒临床医生从多个角度治疗 CRC 患者的抑郁,如增加社会支持和减少述情障碍。