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NACDDB:核酸圆二色性数据库。

NACDDB: Nucleic Acid Circular Dichroism Database.

机构信息

Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, PL-02-109 Warsaw, Poland.

Université Paris-Saclay, CEA, CNRS, LLB, 91191, Gif-sur-Yvette, France.

出版信息

Nucleic Acids Res. 2023 Jan 6;51(D1):D226-D231. doi: 10.1093/nar/gkac829.

Abstract

The Nucleic Acid Circular Dichroism Database (NACDDB) is a public repository that archives and freely distributes circular dichroism (CD) and synchrotron radiation CD (SRCD) spectral data about nucleic acids, and the associated experimental metadata, structural models, and links to literature. NACDDB covers CD data for various nucleic acid molecules, including DNA, RNA, DNA/RNA hybrids, and various nucleic acid derivatives. The entries are linked to primary sequence and experimental structural data, as well as to the literature. Additionally, for all entries, 3D structure models are provided. All entries undergo expert validation and curation procedures to ensure completeness, consistency, and quality of the data included. The NACDDB is open for submission of the CD data for nucleic acids. NACDDB is available at: https://genesilico.pl/nacddb/.

摘要

核酸圆二色性数据库 (NACDDB) 是一个公共存储库,用于存档和免费分发有关核酸的圆二色性 (CD) 和同步辐射 CD (SRCD) 光谱数据,以及相关的实验元数据、结构模型和文献链接。NACDDB 涵盖了各种核酸分子的 CD 数据,包括 DNA、RNA、DNA/RNA 杂交体和各种核酸衍生物。条目链接到原始序列和实验结构数据,以及文献。此外,对于所有条目,都提供了 3D 结构模型。所有条目都经过专家验证和管理程序,以确保包括的数据的完整性、一致性和质量。NACDDB 可提交核酸的 CD 数据。NACDDB 可在以下网址获得:https://genesilico.pl/nacddb/。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4f6/9825466/c0f246311b79/gkac829figgra1.jpg

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