Department of Thoracic Medicine and Surgery, Temple Lung Center, Temple University Hospital, 7 Parkinson Pavilion, 3401 North Broad Street, Philadelphia 19140, USA.
Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Temple Lung Center, Temple University Hospital, 7 Parkinson Pavilion, 3401 North Broad Street, Philadelphia 19140, USA.
Med Clin North Am. 2022 Nov;106(6):1013-1025. doi: 10.1016/j.mcna.2022.07.006. Epub 2022 Oct 4.
Chronic obstructive pulmonary disease (COPD) is the third leading cause of mortality in the United States, behind cardiovascular and malignant disorders. As the understanding of the pathogenesis has evolved, it led to targeting mechanical aspects of the disease to improve patient symptoms and quality of life. Modern management of COPD offers a variety of mechanical and surgical treatments for patients with advanced disease who do not achieve benefit from medical therapy alone. These treatments include therapies aimed at lung volume reduction, through surgical or bronchoscopic techniques. While these techniques are established and have proven benefit, others are still under development. Herein we discuss these techniques, aimed at improving clinician recognition of patients that may benefit from these interventions.
慢性阻塞性肺疾病(COPD)是美国第三大致死原因,仅次于心血管和恶性疾病。随着对发病机制的认识不断发展,针对疾病的机械方面进行治疗以改善患者的症状和生活质量。对于仅通过药物治疗无法获益的晚期 COPD 患者,现代 COPD 管理提供了多种机械和手术治疗方法。这些治疗方法包括通过手术或支气管镜技术来减少肺容积。虽然这些技术已经确立并已证明有效,但其他技术仍在开发中。本文讨论了这些技术,旨在提高临床医生对可能从这些干预中获益的患者的认识。