Department of Medicine, Aga Khan University Hospital, Karachi.
Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
J Pak Med Assoc. 2022 Sep;72(9):1858-1861. doi: 10.47391/JPMA.4281.
Primary Thyroid Lymphoma (PTL) is a rare disease, mostly affecting middle-to-old aged females. It has a strong association with pre-existing thyroiditis, which increases the risk of its development. The disease has been studied in detail in the Western populations. However, there is lack of data for south Asians, especially in Pakistani population. This study was carried out to learn more about the disease characteristics in our area. This was a retrospective study where we reviewed four diagnosed and/or treated cases of primary thyroid Lymphoma at tertiary care hospital of Pakistan (Aga Khan University Hospital), Karachi, Pakistan. Each patient's medical record was reviewed and studied. The participants' average age was 62.8±10.12 years,, with two males and two females. The histology of all of the patients was compatible with the Diffuse B cell Lymphoma subtype. One patient died as a result of complications, one patient was lost to follow up, and the remaining two patients are doing well with no active complaints and are being followed up on a regular basis.
原发性甲状腺淋巴瘤（PTL）是一种罕见疾病，主要影响中老年女性。它与先前存在的甲状腺炎有很强的关联，这增加了其发展的风险。这种疾病在西方人群中已经得到了详细研究。然而，南亚人群的数据缺乏，特别是在巴基斯坦人群中。本研究旨在了解我们地区该疾病的特征。这是一项回顾性研究，我们在巴基斯坦卡拉奇的 Aga Khan 大学医院（一家三级护理医院）回顾性研究了四个确诊和/或治疗的原发性甲状腺淋巴瘤病例。每个患者的病历都进行了回顾和研究。参与者的平均年龄为 62.8±10.12 岁，其中 2 名男性，2 名女性。所有患者的组织学均符合弥漫性 B 细胞淋巴瘤亚型。一名患者因并发症死亡，一名患者失访，其余两名患者情况良好，无明显不适，并定期进行随访。
