Department of Fisheries and Marine Bioscience, Faculty of Biological Science, Jashore University of Science and Technology, Jashore, Bangladesh.
Department of Genetic Engineering and Biotechnology, Faculty of Life and Earth Science, University of Rajshahi, Rajshahi, Bangladesh.
Vet Med Sci. 2023 Mar;9(2):778-801. doi: 10.1002/vms3.979. Epub 2022 Oct 25.
This review aims to provide an update on the current scientific understanding of various aspects of White Spot Syndrome Virus (WSSV) formation, diagnostic procedures, transmission, ecological effects, pathophysiology and management strategies. In terms of production and financial benefits, the WSSV has been the most virulent in shrimp and several other crustacean sectors around the globe. It spreads vertically from diseased broodstock to post-larvae and horizontally by cannibalism, invertebrate vectors, freshwater and sediments. In the transfer of white spot disease (WSD) in newly stocked ponds, the survivability of WSSV in sediment is the most important variable. In typical cultural conditions, it is a highly infectious pathogen capable of inflicting total death within 3-10 days after an outbreak. Some of the current biosecurity strategies used to keep diseases out of shrimp ponds such as pond water disinfection, quarantine of new stocks before stocking and broader usage of specific pathogen-free shrimp. The sequencing and characterisation of various WSSV strains have provided details about pathogen biology, pathogenicity and disease. To develop successful control methods, knowledge of these characteristics is essential. In several shrimp-producing countries in Asia and the Americas, the infections produced by the WSSV have had disastrous socio-economic consequences. As a result of international trade or migration of diseased species, the World Animal Health Organization recognised several illnesses as posing a substantial hazard to farmed shrimp. WSD is receiving much scientific research due to the potential economic effects of the virus. Research is now being done to understand better the molecular biology and pathophysiology of WSSV, as well as how to treat and prevent the virus. However, further study should be conducted in countries with more resilient host species to understand their role in mitigating disease impacts since these revelations may aid in developing a WSD treatment.
本综述旨在提供关于白斑综合征病毒(WSSV)形成、诊断程序、传播、生态影响、病理生理学和管理策略等方面的最新科学认识。就生产和经济利益而言,WSSV 对虾和全球其他几个甲壳类动物部门的危害最为严重。它通过垂直传播从患病亲虾传播到幼体,通过水平传播通过同类相食、无脊椎动物媒介、淡水和沉积物传播。在新投放池塘中转移白斑病(WSD)时,沉积物中 WSSV 的存活能力是最重要的变量。在典型的养殖条件下,它是一种高度传染性病原体,爆发后 3-10 天内可导致全部死亡。目前用于防止虾池疾病的一些生物安全策略,如池塘水消毒、投放前新苗种检疫和更广泛使用无特定病原体虾。对各种 WSSV 菌株的测序和特征分析提供了有关病原体生物学、致病性和疾病的详细信息。为了开发成功的控制方法,了解这些特征是必不可少的。在亚洲和美洲的几个虾生产国,WSSV 感染造成了灾难性的社会经济后果。由于国际贸易或患病物种的迁移,世界动物卫生组织将几种疾病确认为对养殖虾构成重大威胁。由于病毒可能带来的经济影响,WSD 受到了大量科学研究的关注。目前正在进行研究,以更好地了解 WSSV 的分子生物学和病理生理学,以及如何治疗和预防该病毒。然而,由于这些发现可能有助于开发 WSD 治疗方法,因此应该在宿主物种更具弹性的国家进行进一步研究,以了解它们在减轻疾病影响方面的作用。