Department of Neurology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Clin Appl Thromb Hemost. 2022 Jan-Dec;28:10760296221131801. doi: 10.1177/10760296221131801.
Acute ischemic stroke (AIS), characterized by high morbidity and mortality, has imposed a considerable burden on society. Despite rapid development in the treatment of AIS, there is still a high risk of recurrence. Furthermore, there is a time delay in waiting for the results of conventional coagulation tests in candidate patients for intravenous thrombolysis therapy. Heterogeneous responses to antiplatelet, intravascular thrombolysis, and endovascular therapies also worsen the situation. Thromboelastography (TEG), as a global and portable detection method for hemostasis, facilitates clinicians in disease monitoring, treatment evaluation, and prognosis prediction in AIS. In this narrative review, we provided a comprehensive summary of the clinical application of TEG in ischemic stroke and gave insights to further studies.
急性缺血性脑卒中(AIS)具有高发病率和高死亡率的特点,给社会带来了巨大负担。尽管 AIS 的治疗取得了快速进展,但复发风险仍然很高。此外,在等待候选患者进行静脉溶栓治疗的常规凝血检测结果时,存在时间延迟。抗血小板、血管内溶栓和血管内治疗的反应不均一也使情况恶化。血栓弹力图(TEG)作为一种用于止血的全局和便携式检测方法,有助于临床医生监测疾病、评估治疗效果和预测 AIS 的预后。在这篇叙述性综述中,我们全面总结了 TEG 在缺血性脑卒中中的临床应用,并为进一步的研究提供了见解。