George D T, Brewerton T D, Jimerson D C
Psychiatry Res. 1987 Jul;21(3):213-20. doi: 10.1016/0165-1781(87)90025-4.
Clinical symptomatology and diagnostic interview studies suggest that patients with bulimic disorder have some characteristics in common with patients with generalized anxiety disorder or panic disorder. The purpose of this study was to compare sodium lactate-induced physiological responses and anxiety symptoms in hospitalized normal weight bulimic patients and healthy controls. Bulimic patients had significantly elevated anxiety ratings at baseline, and showed a trend toward greater increases in anxiety ratings after lactate administration. Lactate-induced anxiety did not provoke an urge to binge in the bulimic patients. In keeping with the specificity of lactate-induced panic attacks in panic disorder, none of the bulimic subjects experienced a panic attack during lactate infusion.
临床症状学和诊断性访谈研究表明，暴食症患者与广泛性焦虑症或惊恐障碍患者有一些共同特征。本研究的目的是比较住院的正常体重暴食症患者和健康对照者在输注乳酸钠后生理反应和焦虑症状的差异。暴食症患者在基线时焦虑评分显著升高，且在输注乳酸后焦虑评分有进一步升高的趋势。乳酸诱发的焦虑并未引发暴食症患者的暴食冲动。与惊恐障碍中乳酸诱发惊恐发作的特异性一致，在输注乳酸期间，没有一名暴食症患者经历惊恐发作。
