贪食症患者的乳酸输注。

Lactate infusions in patients with bulimia.

作者信息

Lindy D C, Walsh B T, Gorman J M, Roose S P, Gladis M, Devlin M J, Glassman A H

机构信息

Department of Clinical Psychopharmacology, New York State Psychiatric Institute, NY 10032.

出版信息

Psychiatry Res. 1988 Dec;26(3):287-92. doi: 10.1016/0165-1781(88)90123-0.

DOI:10.1016/0165-1781(88)90123-0

PMID:3222393

Abstract

We performed lactate infusions in 18 bulimic patients and 11 normal controls. On the basis of blind ratings, bulimic patients appeared to react to the infusion with greater anxiety than controls. The frequency of lactate-induced panic, per se, was lower in bulimic patients than rates reported for panic disorder patients. However, it would be premature to conclude that bulimia is not a heterogeneous syndrome which includes a group of patients who panic with lactate.

摘要

我们对18名神经性贪食症患者和11名正常对照者进行了乳酸输注。基于盲法评分，神经性贪食症患者在输注时似乎比对照组表现出更大的焦虑。就其本身而言，乳酸诱发惊恐发作的频率在神经性贪食症患者中低于惊恐障碍患者报告的发生率。然而，现在就得出神经性贪食症不是一种异质性综合征（其中包括一组对乳酸产生惊恐反应的患者）的结论还为时过早。