Lindy D C, Walsh B T, Gorman J M, Roose S P, Gladis M, Devlin M J, Glassman A H
Department of Clinical Psychopharmacology, New York State Psychiatric Institute, NY 10032.
Psychiatry Res. 1988 Dec;26(3):287-92. doi: 10.1016/0165-1781(88)90123-0.
We performed lactate infusions in 18 bulimic patients and 11 normal controls. On the basis of blind ratings, bulimic patients appeared to react to the infusion with greater anxiety than controls. The frequency of lactate-induced panic, per se, was lower in bulimic patients than rates reported for panic disorder patients. However, it would be premature to conclude that bulimia is not a heterogeneous syndrome which includes a group of patients who panic with lactate.