Bassett L W, Bunnell D H, Jahanshahi R, Gold R H, Arndt R D, Linsman J
Radiology. 1987 Oct;165(1):95-7. doi: 10.1148/radiology.165.1.3628795.
Mammographic examinations of 169 patients with 172 biopsy-proved carcinomas, and of 194 healthy subjects, were interpreted independently and retrospectively by three experienced mammographers, initially as single-view oblique examinations and 6 months later as two-view oblique-cephalocaudal examinations. For the single-view examinations of the cancer patients, 67% of the cancers were correctly recommended for biopsy, additional views were requested for 23%, and a "negative" interpretation was made for 10%. For the single-view examinations of healthy subjects, biopsy was recommended for 7% and additional views were recommended for 32%. For the two-view examinations of women with cancer, 80% of the cancers were correctly recommended for biopsy, additional views were requested for 4%, and a "negative" interpretation was made for 16%. For two-view examinations of healthy subjects, biopsy was recommended for 7% and additional views were requested for only 5%. The authors conclude that single-view screening should not be performed, because it would lead to an excessive number of "call-back" examinations of healthy patients, producing additional cost and anxiety that would outweigh any theoretical benefit.
169例经活检证实患有172处癌肿的患者以及194名健康受试者接受了乳房X线检查，由三位经验丰富的乳房X线检查医师独立地进行回顾性解读，最初是单视角斜位检查，6个月后是双视角斜位-头足位检查。对于癌症患者的单视角检查，67%的癌症被正确建议进行活检，23%的病例被要求补充检查，10%的病例被解读为“阴性”。对于健康受试者的单视角检查，7%的病例被建议活检，32%的病例被建议补充检查。对于癌症女性患者的双视角检查，80%的癌症被正确建议进行活检，4%的病例被要求补充检查，16%的病例被解读为“阴性”。对于健康受试者的双视角检查，7%的病例被建议活检，仅5%的病例被要求补充检查。作者得出结论，不应进行单视角筛查，因为这将导致对健康患者进行过多的“召回”检查，产生额外的成本和焦虑，而这将超过任何理论上的益处。
