Woodman C B, Threlfall A G, Boggis C R, Prior P
Centre for Cancer Epidemiology, Christie Hospital NHS Trust, Withington, Manchester.
BMJ. 1995 Jan 28;310(6974):224-6. doi: 10.1136/bmj.310.6974.224.
To report the detection rate of interval cancers in women screened by the NHS breast screening programme.
Detection of interval cancers by computer linkage of records held by the screening centres in the North Western Regional Health Authority with breast cancer registrations at the regional cancer registry.
North Western Regional Health Authority.
137,421 women screened between 1 March 1988 and 31 March 1992 who had a negative screening result.
297 invasive interval cancers were detected. The rate of detection of interval cancers expressed as a proportion of the underlying incidence was 31% in the first 12 months after screening, 52% between 12 and 24 months, and 82% between 24 and 36 months.
The incidence of interval cancers in the third year after breast screening approaches that which would have been expected in the absence of screening and suggests that the three year interval between screens is too long.
报告通过英国国家医疗服务体系（NHS）乳房筛查计划接受筛查的女性中，间期癌的检出率。
通过将西北地区卫生局筛查中心保存的记录与地区癌症登记处的乳腺癌登记信息进行计算机关联，来检测间期癌。
西北地区卫生局。
1988年3月1日至1992年3月31日期间接受筛查且筛查结果为阴性的137,421名女性。
检测到297例浸润性间期癌。以潜在发病率的比例表示，间期癌的检出率在筛查后的前12个月为31%，12至24个月为52%，24至36个月为82%。
乳房筛查后第三年间期癌的发病率接近未进行筛查时预期的发病率，这表明筛查间隔三年太长。
