Buishand Floryne O
Department of Clinical Sciences and Services, Royal Veterinary College, Hertfordshire AL9 7TA, UK.
Vet Sci. 2022 Sep 29;9(10):540. doi: 10.3390/vetsci9100540.
The most common pancreatic tumour in dogs is the insulinoma. Canine insulinomas are considered to be malignant in more than 95% of the cases because they almost always tend to metastasise. The diagnosis of an insulinoma requires the demonstration of the simultaneous occurrence of hypoglycaemia and blood insulin levels that are within or above the high end of the reference interval. The staging of canine insulinomas is preferably conducted by contrast-enhanced computed tomography. In general, surgical treatment is the most effective because of it results in long survival times, but many dogs also require medical treatment at some point. The prognosis of canine insulinomas is guarded as clinical hypoglycaemia almost always returns due to metastasis or tumour regrowth. This review aims to provide a summary and update the current recommendations in the veterinary literature for the diagnosis, treatment and prognostication of canine insulinomas.
犬类最常见的胰腺肿瘤是胰岛素瘤。超过95%的犬类胰岛素瘤被认为是恶性的，因为它们几乎总是倾向于转移。胰岛素瘤的诊断需要证明同时出现低血糖以及血液胰岛素水平在参考区间的高端或高于该区间。犬类胰岛素瘤的分期最好通过增强计算机断层扫描进行。一般来说，手术治疗是最有效的，因为它能带来较长的生存时间，但许多犬在某些时候也需要药物治疗。犬类胰岛素瘤的预后不佳，因为临床低血糖几乎总会因转移或肿瘤复发而再次出现。本综述旨在总结并更新兽医文献中关于犬类胰岛素瘤诊断、治疗和预后的当前建议。
