Department of Urology, Jinjiang Municipal Hospital, Quanzhou, Fujian Province, 362000, China.
Department of Urology, Jinjiang Municipal Hospital, Quanzhou, Fujian Province, 362000, China.
Comput Methods Programs Biomed. 2022 Nov;226:107184. doi: 10.1016/j.cmpb.2022.107184. Epub 2022 Oct 18.
To propose a fast detection method for prostate cancer abnormal cells based on deep learning. The purpose of this method is to quickly and accurately locate and identify abnormal cells, so as to improve the efficiency of prostate precancerous screening and promote the application and popularization of prostate cancer cell assisted screening technology.
The method includes two stages: preliminary screening of abnormal cell images and accurate identification of abnormal cells. In the preliminary screening stage of abnormal cell images, ResNet50 model is used as the image classification network to judge whether the local area contains cell clusters. In the another stage, YoloV5 model is used as the target detection network to locate and recognize abnormal cells in the image containing cell clusters.
This detection method aims at the pathological cell images obtained by the membrane method. And the double stage models proposed in this paper are compared with the single stage model method using only the target detection model. The results show that through the image classification network based on deep learning, we can first judge whether there are abnormal cells in the local area. If there are abnormal cells, we can further use the target detection method based on candidate box for analysis, which can reduce the reasoning time by 50% and improve the efficiency of abnormal cell detection under the condition of losing a small amount of accuracy and slightly increasing the complexity of the model.
This study proposes a fast detection method for prostate cancer abnormal cells based on deep learning, which can greatly shorten the reasoning time and improve the detection speed. It is able to improve the efficiency of prostate precancerous screening.
提出一种基于深度学习的前列腺癌异常细胞快速检测方法。该方法的目的是快速准确地定位和识别异常细胞,从而提高前列腺癌癌前筛查的效率,并促进前列腺癌细胞辅助筛查技术的应用和普及。
该方法包括两个阶段:异常细胞图像的初步筛选和异常细胞的准确识别。在异常细胞图像的初步筛选阶段,使用 ResNet50 模型作为图像分类网络,判断局部区域是否包含细胞簇。在另一个阶段,使用 YoloV5 模型作为目标检测网络,定位和识别包含细胞簇的图像中的异常细胞。
该检测方法针对膜法获得的病理细胞图像,将本文提出的双阶段模型与仅使用目标检测模型的单阶段模型方法进行比较。结果表明,通过基于深度学习的图像分类网络,可以首先判断局部区域是否存在异常细胞。如果存在异常细胞,可以进一步使用基于候选框的目标检测方法进行分析,在准确性略有下降和模型复杂度略有增加的情况下,可以将推理时间缩短 50%,提高异常细胞检测的效率。
本研究提出了一种基于深度学习的前列腺癌异常细胞快速检测方法,该方法可以大大缩短推理时间,提高检测速度,提高前列腺癌癌前筛查的效率。