State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China; First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Acta Trop. 2023 Jan;237:106720. doi: 10.1016/j.actatropica.2022.106720. Epub 2022 Oct 23.
West Nile virus is perhaps the widest distributed arbovirus globally, being maintained in nature by transmission among ornithophagic Culex mosquitoes and a wide-variety of birds. A factor contributing to the success of the WNV invasion is the ability of the virus to successfully overwinter. Experimental studies on the preservation and transmission of West Nile virus by Culex pipiens pallens under simulated overwintering conditions have shown that Cx. p. pallens has a preservative effect on West Nile virus under low-temperature conditions. After the temperature rises, the virus reproduces rapidly and can spread to susceptible animals while the mosquitos feed on blood. This research is of great significance for exploring how West Nile virus enters new areas and how the cycle of transmission is maintained China.
西尼罗河病毒可能是全球分布最广泛的虫媒病毒,通过食虫库蚊属和多种鸟类之间的传播在自然界中维持着。该病毒成功越冬的能力是其成功入侵的一个因素。在模拟越冬条件下,对库蚊属按蚊传播西尼罗河病毒的保存和传播的实验研究表明,在低温条件下,库蚊属按蚊对西尼罗河病毒有保存作用。当温度升高时,病毒迅速繁殖,并在蚊子吸血时传播给易感动物。这项研究对于探索西尼罗河病毒如何进入新地区以及传播周期如何维持具有重要意义。