Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Multiple Sclerosis Center, Charles University and General University Hospital in Prague, Katerinska 30, 120 00, Prague, Czech Republic.
MS Rehab Z.S., Prague, Czech Republic.
Dysphagia. 2023 Aug;38(4):1087-1095. doi: 10.1007/s00455-022-10530-5. Epub 2022 Oct 26.
Dysphagia is a common symptom of neurological disease, including multiple sclerosis (MS). The DYsphagia in MUltiple Sclerosis (DYMUS) questionnaire was developed as a screening tool for swallowing problems. The purpose of the present study was to validate the Czech version of the DYMUS questionnaire. We validated the questionnaire on a sample of 435 patients with MS and 135 healthy controls (HC) chosen by accidental sampling from larger, long-term studies conducted by the Prague MS Center. For the purposes of this study, we used both electronic (primary method of distribution) and paper-based (backup) versions of the questionnaire. The internal consistency of the whole scale was satisfactory (Cronbach's α =0.833). The DYMUS mean score in HC was 0.215 (standard deviation [SD] = 0.776). Normative data suggested a cut-off value for dysphagia between 1 and 2 points. Principal component analysis (PCA) showed a two-factor structure of the adapted scale. However, the structure did not completely correspond to the originally proposed dimensions of dysphagia for solids and liquids; our data supported dropout of item Q10. Criterion validity was proved by the difference in dysphagia between HC and patients MS (U = 25,546, p < 0.001) and by a positive correlation with the EDSS (Kendall's tau-b = 0.169, p < 0.001) and other patient-reported outcomes. The Czech version of the DYMUS questionnaire is a valid and reliable tool for evaluating swallowing impairment in Czech-speaking patients with MS. Moreover, the questionnaire can be administered electronically, with a paper-based backup.
吞咽困难是神经系统疾病的常见症状，包括多发性硬化症（MS）。DYsphagia in MUltiple Sclerosis（DYMUS）问卷是作为一种吞咽问题的筛查工具而开发的。本研究的目的是验证捷克语版的 DYMUS 问卷。我们在布拉格多发性硬化症中心进行的较大规模、长期研究中通过偶然抽样选择了 435 名 MS 患者和 135 名健康对照者（HC）的样本中验证了该问卷。在这项研究中，我们同时使用了电子（主要分发方式）和纸质（备份）版本的问卷。整个量表的内部一致性令人满意（Cronbach's α=0.833）。HC 的 DYMUS 平均得分为 0.215（标准差[SD]=0.776）。基于该数据，提出了 1 到 2 分的吞咽困难的正常值。主成分分析（PCA）显示，经过修正的量表具有两个因子结构。然而，该结构并未完全对应最初提出的固体和液体吞咽困难的维度；我们的数据支持放弃第 10 项。通过 HC 和 MS 患者之间的吞咽困难差异（U=25546，p<0.001）以及与 EDSS（Kendall 的 tau-b=0.169，p<0.001）和其他患者报告的结果的正相关，证明了该问卷的标准效度。捷克语版的 DYMUS 问卷是一种评估捷克语 MS 患者吞咽障碍的有效且可靠的工具。此外，该问卷可以通过电子方式进行管理，也可以提供纸质备份。
