孟加拉国一个特大城市2018年登革热疫情概述。
Sketch of 2018 dengue outbreak in a megacity, Bangladesh.
作者信息
Amin Mohammad Robed, Islam Mohammad Rafiqul, Bhuiyan Muktadir, Islam Md Shahnoor, Islam Fathema, Tuli Habiba Jannatun, Nawar Afra, Tabassum Tamanna, Fardous Jannatul, Hasan Mohammad Jahid
机构信息
Department of Medicine, Dhaka Medical College, Dhaka, Bangladesh.
Department of Medicine, Saheed Suhrawardy Medical College, Dhaka, Bangladesh.
出版信息
Trop Med Health. 2022 Oct 26;50(1):80. doi: 10.1186/s41182-022-00470-z.
BACKGROUND
Dengue has become a major public health threat in Bangladesh since 2000, when the first outbreak was reported. Each outbreak has distinct characteristics, and thus, the report of the outbreak helps to understand the disease process and subsequent clinical management of these patients. On that ground, the study was designed to sketch the clinico-epidemiological characteristics of the 2018 dengue outbreak in Bangladesh.
METHODS
This hospital-based cross-sectional study was conducted in one of the largest public medical college hospitals and a single private hospital located in the southern and northern parts of the megacity of the country. A total of 297 confirmed dengue cases were assessed with a preformed pretested questionnaire. Clinico-epidemiological and laboratory parameters were reported along with sociodemographic details. Statistical analysis was performed with SPSS 20.
RESULTS
Male patients were predominantly affected by dengue infection. The mean age of the patients was 31.24 ± 13.99 (SD) years, with a range from 2 to 85 years. Eighty-two percent of patients reported from the Dhaka metropolitan city. The highest percentage of cases (37.1%) was isolated from Bansree, Dhaka city, followed by Rampura (21.4%) and Khilgaon (6.2%). In addition to common symptoms, e.g., fever (90.6%), headache (90.6%), chills (81.8%), anorexia and vomiting (76.4%), backache, and redness of the eyes were two prominent symptoms that affected more than two-thirds of the study population. On the other hand, less common symptoms, such as cough, abdominal pain, and respiratory distress, were present in 39.7%, 33.7%, and 15.5% of patients, respectively. Overall, 17.6% of patients were hypotensive during admission, with a mean systolic blood pressure of 107.65 ± 18.17 (SD) mmHg. Other prominent signs were dehydration (80.5%) and rash (33%).
CONCLUSION
This outbreak was especially characterized by gastrointestinal symptoms, which were predominant along with other typical features.
背景
自2000年首次报告登革热疫情以来，登革热已成为孟加拉国的主要公共卫生威胁。每次疫情都有独特的特征，因此，疫情报告有助于了解疾病过程以及这些患者随后的临床管理。基于此，本研究旨在勾勒出2018年孟加拉国登革热疫情的临床流行病学特征。
方法
本基于医院的横断面研究在该国特大城市南部和北部的一家最大的公立医学院附属医院和一家私立医院进行。使用预先设计并经过预测试的问卷对总共297例确诊登革热病例进行评估。报告了临床流行病学和实验室参数以及社会人口学细节。使用SPSS 20进行统计分析。
结果
男性患者受登革热感染的影响更为严重。患者的平均年龄为31.24±13.99（标准差）岁，年龄范围为2至85岁。82%的患者来自达卡市。病例比例最高的是达卡市的班斯里（37.1%），其次是兰布尔拉（21.4%）和基尔冈（6.2%）。除了常见症状，如发热（90.6%）、头痛（90.6%）、寒战（81.8%）、厌食和呕吐（76.4%）外，背痛和眼睛发红是影响超过三分之二研究人群的两个突出症状。另一方面，咳嗽、腹痛和呼吸窘迫等不太常见的症状分别出现在39.7%、33.7%和15.5%的患者中。总体而言，17.6%的患者入院时血压过低，平均收缩压为107.65±18.17（标准差）mmHg。其他突出体征为脱水（80.5%）和皮疹（33%）。
结论
本次疫情尤其以胃肠道症状为特征，这些症状与其他典型特征一样占主导地位。
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