癌症治疗中的金属基配合物
Metal-Based Complexes in Cancer Treatment.
作者信息
Gamberi Tania, Hanif Muhammad
机构信息
Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Firenze, Italy.
School of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
出版信息
Biomedicines. 2022 Oct 14;10(10):2573. doi: 10.3390/biomedicines10102573.
Abstract
Metal-based complexes contribute a vital part to the available arsenal of cytotoxic agents today [...].
摘要
金属基配合物在当今现有的细胞毒性药物库中起着至关重要的作用[……]。
相似文献
1
Metal-Based Complexes in Cancer Treatment.癌症治疗中的金属基配合物
Biomedicines. 2022 Oct 14;10(10):2573. doi: 10.3390/biomedicines10102573.
2
Metal complexes of curcumin for cellular imaging, targeting, and photoinduced anticancer activity.姜黄素的金属配合物用于细胞成像、靶向和光诱导抗癌活性。
Acc Chem Res. 2015 Jul 21;48(7):2075-83. doi: 10.1021/acs.accounts.5b00127. Epub 2015 Jul 9.
3
Metal-based Complexes as Potential Anti-cancer Agents.金属基配合物作为潜在的抗癌剂。
Anticancer Agents Med Chem. 2022 Aug 4;22(15):2684-2707. doi: 10.2174/1871520622666220331085144.
4
Effects of multidrug resistance (MDR1) P-glycoprotein expression levels and coordination metal on the cytotoxic potency of multidentate (N4O2) (ethylenediamine)bis[propyl(R-benzylimino)]metal(III) cations.
J Med Chem. 1996 Aug 30;39(18):3483-90. doi: 10.1021/jm950823c.
5
Radicals in transition metal catalyzed reactions? transition metal catalyzed radical reactions? a fruitful interplay anyway: part 1. Radical catalysis by group 4 to group 7 elements.过渡金属催化反应中的自由基？过渡金属催化的自由基反应？无论如何，这是一种富有成效的相互作用：第1部分。第4族到第7族元素的自由基催化。
Top Curr Chem. 2012;320:121-89. doi: 10.1007/128_2011_261.
6
Endoplasmic reticulum stress: an arising target for metal-based anticancer agents.内质网应激：金属类抗肿瘤药物的新兴作用靶点。
Chem Soc Rev. 2020 Nov 21;49(22):8113-8136. doi: 10.1039/d0cs00259c. Epub 2020 Jun 29.
7
Synthesis, DFT Calculations, Antiproliferative, Bactericidal Activity and Molecular Docking of Novel Mixed-Ligand Salen/8-Hydroxyquinoline Metal Complexes.新型混合配体席夫碱/8-羟基喹啉金属配合物的合成、DFT 计算、抗增殖、杀菌活性及分子对接。
Molecules. 2021 Aug 4;26(16):4725. doi: 10.3390/molecules26164725.
8
Mitochondria-Targeting Anticancer Metal Complexes.线粒体靶向抗癌金属配合物。
Curr Med Chem. 2019;26(4):694-728. doi: 10.2174/0929867325666180307112029.
9
Some new nano-sized Fe(II), Cd(II) and Zn(II) Schiff base complexes as precursor for metal oxides: Sonochemical synthesis, characterization, DNA interaction, in vitro antimicrobial and anticancer activities.一些新型纳米尺寸的 Fe(II)、Cd(II) 和 Zn(II)希夫碱配合物作为金属氧化物的前体：超声化学合成、表征、DNA 相互作用、体外抗菌和抗癌活性。
Bioorg Chem. 2016 Dec;69:140-152. doi: 10.1016/j.bioorg.2016.10.009. Epub 2016 Nov 1.
10
Synthesis of New Thiourea-Metal Complexes with Promising Anticancer Properties.具有潜在抗癌特性的新型硫脲-金属配合物的合成
Molecules. 2021 Nov 16;26(22):6891. doi: 10.3390/molecules26226891.
引用本文的文献
1
Stoichiometry effect on the structure, coordination and anticancer activity of gold(I/III) bisphosphine complexes.化学计量对金（I/III）双膦配合物的结构、配位及抗癌活性的影响
Dalton Trans. 2025 Jan 28;54(5):2018-2026. doi: 10.1039/d4dt01663g.
2
Cytotoxic Cu(II) Complexes with a Novel Quinoline Derivative Ligand: Synthesis, Molecular Docking, and Biological Activity Analysis.具有新型喹啉衍生物配体的细胞毒性铜（II）配合物：合成、分子对接及生物活性分析
ACS Omega. 2024 May 31;9(23):25014-25026. doi: 10.1021/acsomega.4c02129. eCollection 2024 Jun 11.
3
Complexes of Ruthenium(II) as Promising Dual-Active Agents against Cancer and Viral Infections.钌（II）配合物作为对抗癌症和病毒感染的有前景的双活性药物。
Pharmaceuticals (Basel). 2023 Dec 15;16(12):1729. doi: 10.3390/ph16121729.
4
Metal Chelates of Sulfafurazole Azo Dye Derivative: Synthesis, Structure Affirmation, Antimicrobial, Antitumor, DNA Binding, and Molecular Docking Simulation.磺胺异恶唑偶氮染料衍生物的金属螯合物：合成、结构确证、抗菌、抗肿瘤、DNA结合及分子对接模拟
Bioinorg Chem Appl. 2023 Apr 22;2023:2239976. doi: 10.1155/2023/2239976. eCollection 2023.
本文引用的文献
1
Photoactive and Luminescent Transition Metal Complexes as Anticancer Agents: A Guiding Light in the Search for New and Improved Cancer Treatments.作为抗癌剂的光活性和发光过渡金属配合物：寻找新型改良癌症治疗方法的指引之光。
Biomedicines. 2022 Mar 1;10(3):578. doi: 10.3390/biomedicines10030578.
2
Synthesis, Structure, and Antiproliferative Action of 2-Pyridyl Urea-Based Cu(II) Complexes.基于2-吡啶基脲的铜（II）配合物的合成、结构及抗增殖作用
Biomedicines. 2022 Feb 16;10(2):461. doi: 10.3390/biomedicines10020461.
3
PdSpermine Complex Shows Cancer Selectivity and Efficacy to Inhibit Growth of Triple-Negative Breast Tumors in Mice.钯精胺配合物对小鼠三阴性乳腺癌肿瘤生长具有癌症选择性和抑制作用。
Biomedicines. 2022 Jan 19;10(2):210. doi: 10.3390/biomedicines10020210.
4
In Vitro Nephrotoxicity Studies of Established and Experimental Platinum-Based Compounds.已确立的和实验性铂类化合物的体外肾毒性研究
Biomedicines. 2021 Aug 18;9(8):1033. doi: 10.3390/biomedicines9081033.
5
Auphen and Auoxo6, Two Dinuclear Oxo-Bridged Gold(III) Compounds, Induce Apoptotic Signaling in Human Ovarian A2780 Cancer Cells.奥芬和奥克索6，两种双核氧桥联金（III）化合物，在人卵巢A2780癌细胞中诱导凋亡信号。
Biomedicines. 2021 Jul 23;9(8):871. doi: 10.3390/biomedicines9080871.
6
Modulation of Intracellular Copper Levels as the Mechanism of Action of Anticancer Copper Complexes: Clinical Relevance.调节细胞内铜水平作为抗癌铜配合物的作用机制：临床相关性
Biomedicines. 2021 Jul 21;9(8):852. doi: 10.3390/biomedicines9080852.
7
Noble Metals for Modern Implant Materials: MOCVD of Film Structures and Cytotoxical, Antibacterial, and Histological Studies.用于现代植入材料的贵金属：薄膜结构的金属有机化学气相沉积及细胞毒性、抗菌和组织学研究
Biomedicines. 2021 Jul 21;9(8):851. doi: 10.3390/biomedicines9080851.
8
Strategies for the Improvement of Metal-Based Chemotherapeutic Treatments.改善金属基化疗治疗的策略。
Biomedicines. 2021 May 4;9(5):504. doi: 10.3390/biomedicines9050504.
9
High Antiproliferative Activity of Hydroxythiopyridones over Hydroxypyridones and Their Organoruthenium Complexes.羟基硫代吡啶酮相对于羟基吡啶酮及其有机钌配合物具有高抗增殖活性。
Biomedicines. 2021 Jan 27;9(2):123. doi: 10.3390/biomedicines9020123.
Zotero 插件