Luecke Christoph, Schnetzke Marc, Weiss Christel, Studier-Fischer Stefan, Guehring Thorsten, Gruetzner Paul A, Porschke Felix
BG Trauma Center Ludwigshafen, Heidelberg University Hospital, Ludwig-Guttmann-Straße 13, 67071 Ludwigshafen, Germany.
German Joint Center, Atos Clinic, Bismarckstraße 9-15, 69115 Heidelberg, Germany.
Biology (Basel). 2022 Sep 22;11(10):1381. doi: 10.3390/biology11101381.
(1) Many biomechanical studies are performed using fresh frozen cadavers or embalmed specimens, although the biomechanical characteristics do not match the characteristics of in vivo tendons. Therefore, a fresh in vivo-like cadaver model has been introduced recently. As a limitation for studies with fresh cadavers, must be considered. The aim of this study was to evaluate the impact of the biomechanical properties and time of occurrence of in a fresh cadaver model. (2) For this study, 15 fresh porcine cadaver shoulders were used in an established biomechanical in vitro model to evaluate the onset of . Measurements took place at ten points of time (t1-t10) beginning 103 min post mortem (pm). The mobility of the supraspinatus tendon was measured in Newton (N) with a modified sensor-enhanced arthroscopic grasper. (3) The mean load measured at the time point t1 was 28.0 ± 11.2 N. The first significant decrease of mobility occurred 151 min post mortem (t4) at a mean load of 30.2 ± 13.7 N. From 227 min pm to 317 min pm, there was no further significant increase. (4) Tendon mobility decreases significantly within the first three hours after the killing. Therefore, reliable results can be obtained within 150 min post mortem before the onset of alters the biomechanical properties.
(1) 许多生物力学研究是使用新鲜冷冻尸体或防腐标本进行的，尽管其生物力学特性与体内肌腱的特性不匹配。因此，最近引入了一种类似新鲜活体的尸体模型。作为使用新鲜尸体进行研究的一个限制因素，必须予以考虑。本研究的目的是评估在新鲜尸体模型中生物力学特性和[此处缺失关键信息]发生时间的影响。(2) 对于本研究，在一个既定的生物力学体外模型中使用了15个新鲜猪尸体肩部来评估[此处缺失关键信息]的发生情况。测量在死后103分钟（pm）开始的十个时间点（t1 - t10）进行。使用改良的传感器增强关节镜抓钳以牛顿（N）为单位测量冈上肌腱的活动度。(3) 在时间点t1测量的平均负荷为28.0 ± 11.2 N。活动度的首次显著下降发生在死后151分钟（t4），平均负荷为30.2 ± 13.7 N。从死后227分钟到317分钟，没有进一步的显著增加。(4) 肌腱活动度在处死后的前三小时内显著下降。因此，在死后150分钟内，在[此处缺失关键信息]改变生物力学特性之前，可以获得可靠的结果。
