Natali F, Marotel C, Heyraud J D, Vaylet F, Bonnet D, Herning R, L'Her P, de Muizon H, Allard P
Rev Pneumol Clin. 1987;43(3):145-50.
Twelve cases of bifocal and bilateral bronchial carcinoma are presented. The two tumours developed successively in 6 cases and simultaneously in 6 cases. Patients' mean age (60 years) was the same as in other lung cancers. Four out of 12 patients produced a history of old ENT or skin cancer. In 11 out of 12 cases the second tumour, undetectable by radiology, was discovered at bronchoscopy. In 2 patients the two tumours had a different histology: adenocarcinoma and squamous cell tumour. In all other cases, both tumours were of the squamous cell type. Treatment of the second contralateral tumour was difficult to determine, especially when the first tumour had been widely excised. However, radiotherapy focused on small endobronchial tumours seemed to give interesting results.
本文报告了12例双灶性双侧支气管癌病例。6例患者的两个肿瘤先后发生，6例患者的两个肿瘤同时发生。患者的平均年龄（60岁）与其他肺癌患者相同。12例患者中有4例有既往耳鼻喉科或皮肤癌病史。12例患者中有11例在支气管镜检查时发现了放射学检查无法检测到的第二个肿瘤。2例患者的两个肿瘤组织学不同：腺癌和鳞状细胞瘤。在所有其他病例中，两个肿瘤均为鳞状细胞类型。对侧第二个肿瘤的治疗很难确定，尤其是当第一个肿瘤已被广泛切除时。然而，针对小的支气管内肿瘤的放射治疗似乎取得了令人感兴趣的结果。
