Center for Toxicology and Health Risk Studies (CORE), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia.
Institute of Sustainable Energy, Department of Electrical & Electronics, Universiti Tenaga Nasional, Kajang 43000, Malaysia.
Int J Environ Res Public Health. 2022 Oct 11;19(20):12997. doi: 10.3390/ijerph192012997.
Since the year 2020, coronavirus disease 2019 (COVID-19) has emerged as the dominant topic of discussion in the public and research domains. Intensive research has been carried out on several aspects of COVID-19, including vaccines, its transmission mechanism, detection of COVID-19 infection, and its infection rate and factors. The awareness of the public related to the COVID-19 infection factors enables the public to adhere to the standard operating procedures, while a full elucidation on the correlation of different factors to the infection rate facilitates effective measures to minimize the risk of COVID-19 infection by policy makers and enforcers. Hence, this paper aims to provide a comprehensive and analytical review of different factors affecting the COVID-19 infection rate. Furthermore, this review analyses factors which directly and indirectly affect the COVID-19 infection risk, such as physical distance, ventilation, face masks, meteorological factor, socioeconomic factor, vaccination, host factor, SARS-CoV-2 variants, and the availability of COVID-19 testing. Critical analysis was performed for the different factors by providing quantitative and qualitative studies. Lastly, the challenges of correlating each infection risk factor to the predicted risk of COVID-19 infection are discussed, and recommendations for further research works and interventions are outlined.
自 2020 年以来,新型冠状病毒病 2019(COVID-19)已成为公众和研究领域讨论的主要话题。人们对 COVID-19 的多个方面进行了深入研究,包括疫苗、传播机制、COVID-19 感染的检测及其感染率和相关因素。公众对 COVID-19 感染因素的认识使公众能够遵守标准操作程序,而充分阐明不同因素与感染率的相关性有助于决策者和执行者采取有效措施将 COVID-19 感染的风险降至最低。因此,本文旨在对影响 COVID-19 感染率的不同因素进行全面和分析性的综述。此外,本综述分析了直接和间接影响 COVID-19 感染风险的因素,例如身体距离、通风、口罩、气象因素、社会经济因素、疫苗接种、宿主因素、SARS-CoV-2 变体以及 COVID-19 检测的可用性。通过提供定量和定性研究对不同因素进行了批判性分析。最后,讨论了将每个感染风险因素与 COVID-19 感染的预测风险相关联的挑战,并概述了进一步研究工作和干预措施的建议。