Hilaris B S, Martini N, Wong G Y, Nori D
Surg Clin North Am. 1987 Oct;67(5):965-77. doi: 10.1016/s0039-6109(16)44335-5.
It appears that combined preoperative radiation and surgery continue to offer the best survival results in patients with superior sulcus tumors. Patients with involvement of the brachial plexus, Horner's syndrome, rib invasion, and ipsilateral neck node metastases are still candidates for combined modality therapy, with expectations of survival of about 30 to 40 per cent. However, those presenting with invasion of vertebrae, involvement of subclavian vessels, and mediastinal lymph node metastases do poorly. In this latter group, treatment by high-dose external radiation alone may prove to be as effective as combined modality treatment.
对于肺上沟瘤患者，术前放疗与手术相结合似乎仍是能带来最佳生存结果的治疗方式。伴有臂丛神经受累、霍纳综合征、肋骨侵犯及同侧颈部淋巴结转移的患者仍适合接受综合治疗，预期生存率约为30%至40%。然而，那些出现椎体侵犯、锁骨下血管受累及纵隔淋巴结转移的患者预后较差。在后一组患者中，单纯高剂量外照射治疗可能与综合治疗同样有效。
