Hernández Alicia, Muñoz Elena, Ramiro-Cortijo David, Spagnolo Emanuela, Lopez Ana, Sanz Angela, Redondo Cristina, Salas Patricia, Cristobal Ignacio
Department of Obstetrics and Gynecology, Hospital Universitario La Paz, Paseo de la Castellana, 261, 28046 Madrid, Spain.
Research Institute of Hospital Universitario La Paz (IdiPaz), C/ Pedro Rico 6, 28019 Madrid, Spain.
J Clin Med. 2022 Oct 20;11(20):6192. doi: 10.3390/jcm11206192.
The quality of life (QoL) of women who have been surgically treated for endometriosis may be severely impaired. Therefore, QoL can be a determining factor in the recovery of these patients. The aims of this study were to evaluate if the QoL of women surgically treated for deep endometriosis differs from a healthy age-matched population from Catalonia (Spain) and to analyze the QoL of these women considering concomitant events. This is an observational cross-sectional study, where 112 women (between 18 and 48 years old), with endometriosis treated by surgery at Hospital Universitario La Paz (Madrid, Spain), were enrolled to assess the QoL using the second version of the 12-item short form (SF-12) questionnaire. The QoL in these women were tested against a reference population of healthy women using a standardized one-sample comparison method. In addition, the QoL was compared according to the pathophysiology and type of surgery. In women with endometriosis, the physical health component, but not mental health component, was positively correlated with age (r = 0.19; -Value = 0.048). In addition, physical (20.3 ± 29.2) and social functions (29.7 ± 38.3) and the overall physical health component (37.8 ± 19.4) were significantly lower than the reference population. On the contrary, the body pain (64.1 ± 41.2), emotional role (62.5 ± 42.2), mental health (54.4 ± 26.0), vitality (59.3 ± 31.2), and the overall mental health component (59.4 ± 26.6) had significantly higher scores than the reference. The anatomical compartment of endometriosis, reintervention, bowel nodule resection, and fertility preservation did not show statistical differences in QoL. Women with deep endometriosis had worse physical and social functions, and the overall physical health, compared to the norm in Spanish women. Bodily pain, emotional role, vitality, and the overall mental health improved. These areas could be considered protective factors in this disease. Considering the importance of QoL in adjustments in mental and physical health, it would be necessary to improve these areas of QoL in women surgically treated for deep endometriosis.
接受过子宫内膜异位症手术治疗的女性的生活质量（QoL）可能会受到严重损害。因此，生活质量可能是这些患者康复的一个决定性因素。本研究的目的是评估接受深部子宫内膜异位症手术治疗的女性的生活质量与来自加泰罗尼亚（西班牙）的年龄匹配的健康人群是否不同，并分析这些女性在考虑伴随事件时的生活质量。这是一项观察性横断面研究，招募了112名年龄在18至48岁之间、在西班牙马德里拉巴斯大学医院接受过子宫内膜异位症手术治疗的女性，使用12项简短形式健康调查（SF-12）问卷第二版来评估她们的生活质量。使用标准化的单样本比较方法，将这些女性的生活质量与健康女性的参考人群进行比较。此外，还根据病理生理学和手术类型对生活质量进行了比较。在患有子宫内膜异位症的女性中，身体健康成分与年龄呈正相关（r = 0.19；P值 = 0.048），但心理健康成分与年龄无此相关性。此外，身体功能（20.3 ± 29.2）、社会功能（29.7 ± 38.3）和总体身体健康成分（37.8 ± 19.4）显著低于参考人群。相反，身体疼痛（64.1 ± 41.2）、情感角色（62.5 ± 42.2）、心理健康（54.4 ± 26.0）、活力（59.3 ± 31.2）和总体心理健康成分（59.4 ± 26.6）得分显著高于参考人群。子宫内膜异位症的解剖部位、再次干预、肠结节切除和生育保留在生活质量方面未显示出统计学差异。与西班牙女性的正常水平相比，患有深部子宫内膜异位症的女性身体和社会功能以及总体身体健康状况较差。身体疼痛、情感角色、活力和总体心理健康状况有所改善。这些方面可被视为该疾病的保护因素。考虑到生活质量在身心健康调整中的重要性，有必要改善接受深部子宫内膜异位症手术治疗的女性在这些生活质量方面的状况。
