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子宫内膜异位症与不孕症

Endometriosis and Infertility.

作者信息

Ferrell Kate, Rohlfs Angelina, Hansen Keith, Von Wald Tiffany

机构信息

University of South Dakota Sanford School of Medicine.

Sanford Health, Sioux Falls, South Dakota.

出版信息

S D Med. 2020 Aug;73(8):350-355.

Abstract

Endometriosis is a disease that affects a significant portion of reproductive age women. It can cause chronic pelvic pain and has been associated with subfertility. Treatment options differ depending on a patient's reproductive goals; women who do not desire pregnancy are treated with hormonal medications including combined oral contraceptives, progestin only pills or intrauterine devices, gonadotropin releasing hormone agonists and antagonists, and danocrine. The treatment options for women desiring pregnancy are more limited and most often include surgery to improve pain symptoms and increase the chances of conception. However, the chance of a successful pregnancy does not increase with each concurrent endometriosis surgery, and in fact may merely delay fertility treatment using assisted reproductive technology.

摘要

子宫内膜异位症是一种影响相当一部分育龄妇女的疾病。它会导致慢性盆腔疼痛,并与生育力低下有关。治疗方案因患者的生育目标而异;不想要怀孕的女性采用激素药物治疗,包括复方口服避孕药、仅含孕激素的药丸或宫内节育器、促性腺激素释放激素激动剂和拮抗剂以及达那唑。想要怀孕的女性的治疗选择更为有限,通常包括手术以改善疼痛症状并增加受孕几率。然而,每次同时进行子宫内膜异位症手术,成功怀孕的几率并不会增加,事实上可能只是推迟了使用辅助生殖技术的生育治疗。

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