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肝移植分配的当前方法

Current Approaches in the Allocation of Liver Transplantation.

作者信息

Ionescu Vlad Alexandru, Diaconu Camelia Cristina, Bungau Simona, Jinga Viorel, Gheorghe Gina

机构信息

"Prof. Dr. Theodor Burghele" Clinical Hospital, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, Romania.

Department of Gastroenterology, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania.

出版信息

J Pers Med. 2022 Oct 6;12(10):1661. doi: 10.3390/jpm12101661.

DOI:10.3390/jpm12101661
PMID:36294801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9605642/
Abstract

In recent decades, important advances have been made in the field of liver transplantation. One of the major problems remaining in this area is the small number of donors. Thus, recent data bring multiple updates of the indications and contraindications of this therapeutic method. The main goal is to increase the number of patients who can benefit from liver transplantation, a therapeutic method that can improve life expectancy and the quality of life of patients with end-stage liver disease. Another goal in the management of these patients is represented by the optimal care of those on the waiting list during that period. A multidisciplinary team approach is necessary to obtain the best results for both the donor and the recipient.

摘要

近几十年来,肝移植领域取得了重要进展。该领域仍然存在的主要问题之一是供体数量少。因此,近期的数据带来了这种治疗方法适应证和禁忌证的多项更新。主要目标是增加能够从肝移植中获益的患者数量,肝移植是一种能够提高终末期肝病患者预期寿命和生活质量的治疗方法。对这些患者进行管理的另一个目标是在此期间对等待名单上的患者进行最佳护理。需要采用多学科团队方法,以便供体和受体都能获得最佳结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1f/9605642/63bb08c8a324/jpm-12-01661-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1f/9605642/79eaeb2334d2/jpm-12-01661-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1f/9605642/63bb08c8a324/jpm-12-01661-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1f/9605642/79eaeb2334d2/jpm-12-01661-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac1f/9605642/63bb08c8a324/jpm-12-01661-g002.jpg

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本文引用的文献

1
Medical adherence and liver transplantation: a brief review.医疗依从性与肝移植:简要综述
Can Liver J. 2021 Feb 24;4(1):8-15. doi: 10.3138/canlivj-2020-0016. eCollection 2021 Winter.
2
Liver Transplantation for Hepatocellular Carcinoma: How Should We Improve the Thresholds?肝细胞癌的肝移植:我们应如何提高标准?
Cancers (Basel). 2022 Jan 14;14(2):419. doi: 10.3390/cancers14020419.
3
Expanding Donor Selection and Recipient Indications for Living Donor Liver Transplantation.扩大活体肝移植供者选择和受者适应证。
Clin Liver Dis. 2021 Feb;25(1):121-135. doi: 10.1016/j.cld.2020.08.011. Epub 2020 Oct 7.
4
Organ donation and transplantation: a multi-stakeholder call to action.器官捐赠与移植:多方利益相关者的行动呼吁。
Nat Rev Nephrol. 2021 Aug;17(8):554-568. doi: 10.1038/s41581-021-00425-3. Epub 2021 May 5.
5
Long-term outcomes of liver transplant recipients followed up in non-transplant centres: Care closer to home.非移植中心随访的肝移植受者的长期结局:在家门口接受关怀。
Clin Med (Lond). 2021 Jan;21(1):e32-e38. doi: 10.7861/clinmed.2020-0609.
6
The endless history or search for the true role of alloantibodies in liver transplantation.关于同种异体抗体在肝移植中真正作用的无尽历史或探索。
Clin Res Hepatol Gastroenterol. 2021 Jul;45(4):101544. doi: 10.1016/j.clinre.2020.09.005. Epub 2020 Oct 17.
7
Prognosis of Split Liver Transplantation Compared with Whole Liver Transplantation in Adult Patients: Single-center Results under the Korean MELD Score-based Allocation Policy.成人患者劈离式肝移植与全肝移植预后的比较:韩国基于 MELD 评分分配政策的单中心结果。
J Korean Med Sci. 2020 Sep 21;35(37):e304. doi: 10.3346/jkms.2020.35.e304.
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Evolution of Liver Transplant Selection Criteria and U.S. Allocation Policy for Patients with Hepatocellular Carcinoma.肝细胞癌患者肝移植选择标准及美国分配政策的演变
Semin Liver Dis. 2020 Nov;40(4):358-364. doi: 10.1055/s-0040-1709492. Epub 2020 Sep 17.
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J Formos Med Assoc. 2021 Feb;120(2):794-803. doi: 10.1016/j.jfma.2020.08.019. Epub 2020 Aug 26.
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Selection for Liver Transplantation: Indications and Evaluation.肝移植的选择:适应证与评估
Curr Hepatol Rep. 2020;19(3):203-212. doi: 10.1007/s11901-020-00527-9. Epub 2020 Jun 19.